Evaluation of the Relationship Between Duration of Smoking and Clinical and Pathologic Characteristics of Bladder Cancer at Diagnosis
Journal Title: Üroonkoloji Bülteni - Year 2017, Vol 16, Issue 4
Abstract
Objective In this study, we aimed to evaluate the relationship between the duration of smoking and clinical and pathological characteristics of malignant bladder cancer at diagnosis. Materials and Methods In this study, a total of 41 patients who were diagnosed with primary bladder cancer and underwent transurethral resection of bladder tumor in our clinic were included in this study. Clinical and pathological features of bladder tumor such as demographic data, smoking status and tumor size, cystoscopic appearance, tumor grade and grade, presence of lamina propria invasion in histopathological examination, presence of necrosis and inflammation were obtained from medical records. The association of these properties with smoking was evaluated retrospectively. Results In this study, mean age of patients was determined to be 69.07 years and mean duration of smoking was 49.8 pack-years. We demonstrated that there was a statically significant relationship between duration of smoking and size of tumors, histological grade and grade of the tumor, solid appearance of the tumor, lamina propria invasion of the tumor, squamous differentiation of the tumor, and presence of histopathological inflammation and necrosis in the tumor. Conclusion The duration of smoking in patients with bladder cancer, may be an important factor that gives information about aggressivity of tumors at the diagnosis to urologist and pathologist.
Authors and Affiliations
Bora İrer, Filiz Dağ, Güven Aslan
Keywords
Related Articles
- EP ID EP369501
- DOI 10.4274/uob.870
- Views 78
- Downloads 0
The Effect of Framingham Score on the Oncological Outcomes in Localized (T1-T2 Stage) Renal Cell Carcinoma Patients
Objective: To evaluate the effect of cardiovascular disease risk on local recurrence, distant metastasis development and cancer-specific survival in patients with localized (stage 1 and 2) renal cell carcinoma (RCC). Mat...
Initial Outcomes and Assessment of the Transperineal Multiparametric-Magnetic Resonance Imaging/Ultrasonography Fusion Biopsy Method in Diagnosing Clinically-significant Prostate Cancer
Objective: In this study, it was aimed to investigate the success of transperineal multiparametric magnetic resonance imaging (mp-MRI)/transrectal ultrasonography (USG) fusion prostate biopsy method in prostate cancer di...
Magnetic Resonance - Transrectal Ultrasound Fusion Guided Prostate Biopsy
Prostate has remained as the single solid organ for which biopsy cannot be performed from a lesion for decades. Lately, the groundbreaking magnetic resonance imaging (MRI) techniques have emerged to scan prostate cancer...
Association between Hormonal Evaluation Before Prostate Needle Biopsy and Locally Advanced Prostate Cancer
Objective: In this study, patients hormonally evaluated before prostate needle biopsy were considered among the ones who underwent radical prostatectomy (RRP) due to prostate adenocarcinoma and had locally advanced patho...
Controversies in Radical Cystectomy: Meta-Analysis and Systemic Comparison of Open Surgery with Laparoscopic and Robotic Surgery
Open radical cystectomy (ORC) is the standard treatment modality in high-risk non-muscle-invasive and invasive bladder carcinoma. Although it has some advantages, oncologic outcomes of ORC are associated with high morbid...