Evaluation of Thyroid Hormones Level in Sudanese Women with Polycystic Ovarian Syndrome
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 3
Abstract
Polycystic ovary syndrome (PCOS) is commonly associated with endocrine, metabolic, cardiovascular and other morbidities. However its association with autoimmune diseases is still controversial. The aim of this study was to evaluate the levels of thyroid hormones and it's antibodies in women with PCOS in Sudan. The method was Ninety female patients with PCOS based on Rotterdam criteria. Together with ninety healthy volunteer females included as controls. Serum levels of Thyroid Stimulating Hormone (TSH), Free Thyroxine (Free T4), Free Triiodothyronine (Free T3) and anti-thyro peroxidase antibody (anti-TPO Ab) were tested in the two groups. In results a significant increase was found in TSH and anti-TPO Ab (P<0.05) along with a significant decrease in free T3 and free T4 in PCOS females matched against controls (P<0.05). In conclusion the data suggest that hypothyroidism related to PCOS, and this hypothyroidism could result in auto immune disease. More studies should be carried to reveal the precise relationship of hypothyroidism in the context of PCOS. Thyroid hormones, polycystic ovarian syndrome, anti-thyro peroxidase antibody, autoimmune disease.
Authors and Affiliations
Mohammed Abbas Osman Abuzaid, Nassr Eldin M. A. Shrif
Keywords
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