Evaluation of Tp-e interval and Tp-e/ QTc ratio in patients with mild to moderate psoriasis
Journal Title: The European Research Journal - Year 2016, Vol 2, Issue 1
Abstract
Objectives. Many systemic diseases including cardiovascular disturbances have been described in psoriatic patients. In the previous studies, left ventricle (LV) subclinical myocardial dysfunction was reported in the psoriasis patients. The T-wave peak to end (Tp-e) interval is a relatively new marker for ventricular arrhythmogenesis and repolarization heterogeneity. Prolongation of this interval represents a period of potential vulnerability to ventricular arrhythmias. However, there is no information available assessing the Tp-e interval and related calculations in patients with psoriasis disease. The aim of this study was to evaluate ventricular repolarization in patients with psoriasis disease by using QT, corrected QT (QTc) and Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio. Methods. In this study, retrospective analysis of 30 patients who underwent the psoriasis treatment and of 30 healthy individuals was performed. The severity of the disease was evaluated by the “Psoriasis Area and Severity Index”. QT, corrected QT (QTc), Tp-e interval and Tp-e/QT ratio were measured by means of the 12-lead electrocardiogram. Left ventricular function was evaluated by echocardiography. Results. Baseline characteristics and QT and QTc intervals were similar in both groups. No difference was detected between the groups with regards to Tp-e interval (83.0±9 vs 82.3±10; p=0.81), Tp-e/QT (0.22±0.03 vs 0.23±0.04; p=0.3) and Tp-Te/QTc (0.20±0.04 vs 0.19±0.04; p=0.77). Conclusions. These findings suggest that ventricular repolarization in mild to moderate psoriasis patients might be unimpaired. Larger samples and severe degree psoriasis patients are needed to evaluate the arrhythmia risk in psoriasis patients.
Authors and Affiliations
Ozlem Arican Ozluk, Mustafa Yilmaz, Dursun Topal, Erhan Tenekecioglu, Selcuk Kanat, Fahriye Vatansever, Tezcan Peker, Kemal Karaagac, Bedrettin Boyraz
Keywords
Related Articles
- EP ID EP194567
- DOI 10.18621/eurj.2016.2.1.46
- Views 91
- Downloads 0
Intrathoracic extramedullary hematopoiesis as a posterior mediastinal tumor: a case report
Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. Usually it is diagnosed incidentally and very rarely it presents as...
Unnecessary computed tomography and magnetic resonance imaging rates in a tertiary care hospital
Objective. The actual rate of unnecessary imaging is unknown in our country. In this study we aimed to detect unnecessary computed tomography (CT) and magnetic resonance imaging (MRI) rates and the radiological quality o...
Management of traumatic pneumothorax in isolated blunt chest trauma
Objectives: Pneumothorax is an important complication of blunt chest trauma. The aim of this study was to report our experience in treatment strategy and outcomes of traumatic pneumothorax. Methods: A total of 78 patien...
Effect of hospital ethical climate on the nurses' moral sensitivity
Objectives: The study determines the effects of the hospitals ethical climate on the moral sensitivity of nurses. Methods: The study design is descriptive and correlational. The data was obtained from 99 nurses who volu...
A new etiology for variant of Guillain-Barré syndrome: bariatric surgery
Bariatric surgery is an effective treatment for obesity. However, the number of acute or chronic neurological complications after bariatric surgery, including Guillain-Barré syndrome, is increasingly reported. We present...