Evaluation of Urinary Calcium Creatinine Ratio in Pre-Eclampsia
Journal Title: National Journal of Laboratory Medicine - Year 2016, Vol 5, Issue 2
Abstract
Introduction: Hypertensive disorder complicates the pregnancy. The exact aetiology of hypertensive disorders of the pregnancy is still unknown and management is controversial. Aim: To evaluate the role of urinary calcium creatinine (CCR) as an marker in early diagnosis of pre-eclampsia. Materials and Methods: Urinary calcium creatinine ratio was determined in a random sample of urine in100 patients of pre-eclampsia (Study group) and 100 normotensive pregnant (Control group) patients of gestational age 20- 36 weeks. Cut off value for CCR was taken as ≤ 0.04. Comparative study was done by using chi-square test. Results: In study group, 89% of the cases had urinary CCR ≤ 0.04. Similarly, amongst the controls only 6% of the cases had CCR ≤ 0.04. Statistically, CCR as high risk factor for early diagnosis of pre-eclampsia was significant (p<0.001 and ‘r’ = 0.169). Conclusion: The result showed lower urinary calcium excretion and low CCR in pre-eclamptic patients than normotensive pregnant women.
Authors and Affiliations
Dr. Indu Prasad, Dr. Bandana Kumari, Dr. Achal Narayan Roy, Dr. Pritam Prakash
Keywords
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