Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital
Journal Title: National Journal of Laboratory Medicine - Year 2017, Vol 6, Issue 4
Abstract
Introduction: Vitamin D has been implicated to play a very important role in different types of cancers due to its pleotropic effects such as cell proliferation, cell differentiation, apoptosis etc. The implications of vitamin D deficiency are more evident in breast, prostate and colorectal cancer. Studies have revealed vitamin D supplementation reduces the risk of Breast cancer. Aim: The main objective of our study was to find out whether low serum 25-hydroxy vitamin D levels was associated with breast cancer. Materials and Methods: Study group included 25 diagnosed cases of breast cancer. Equal number of age and sex matched healthy persons were included in the control group. Serum 25- hydroxy vitamin D was estimated by electrochemiluminiscence immunoassay. Results: Mean vitamin D levels were low in breast cancer patients, when compared to controls (p-value < 0.05),which shows that low vitamin D levels are associated with increased risk of breast cancer. Conclusion: Our study showed that low levels of vitamin D are associated with breast cancer when compared to apparently healthy controls. Estimation of serum vitamin D in patients with breast cancer might help in the early diagnosis and treatment of breast cancer.
Authors and Affiliations
Dr. MN Suma, Dr. Swetha NK, Dr. Parveen Doddamani, Dr. Binay Kumar Yadav, Dr. Akash R
Keywords
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- EP ID EP376747
- DOI 10.7860/NJLM/2017/31900:2256
- Views 104
- Downloads 0
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