EVALUATION THE EFFECT OF THE MALARIA PARASITE ON PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME LEVELS AMONG SUDANESE PATIENT IN KHARTOUM STATE- SUDAN.

Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 9

Abstract

The hemostatic alterations play an important role in malaria pathogenesis and in the progression of disease. In severe infection the accelerated coagulation cascade activity with accelerated fibrinogen turnover increase the bleeding tendency and may lead to DIC. The present study was aimed to determine the effect of malaria parasites on Prothrombin Time and Activated Partial Thromboplastin Time Levels. A single citrated blood sample of patients diagnosed with malaria was analysed in semi- automated coagulation analyzer at the time of presentation, the values were compared with healthy controls. Data was analyzed by mean standard deviation and by ?t? test using SPSS software version 16. PT and APTT were significantly raised in cases when compared to control group, prolonged APTT is observed in 44% (P.value.001) and prolonged PT is observed in 43% of cases (P. value .016), the mean of PT (15.73 sec), and the mean of APTT (40.24 sec) in cases group. The mean of PT and APTT in control group, (13.94 sec), (30.87 sec) respectively. This study concluded that malaria infection altered the blood coagulation mechanism causing significant prolongation in PT and APTT.

Authors and Affiliations

Sarah Mahmoud Abdabagi, Fayhaa Mohammed Altayeb, Ahmed BakheetAbdAlla, RaniaAbdAlrhaman Osman, Ali ElaminNasir.

Keywords

Related Articles

H. PYLORI GASTRITIS IN PATIENT WITH ACTIVE DUODENAL ULCER IN AL-YARMUK HOSPITAL.

Background: It is estimated that 50% of the world?s population is infected by H pylori. It is isolated from the antrum of patient with active chronic gastritis, the organism has been demonstrated in the antrum in most pa...

PERIODONTAL STATUS OF PATIENTS WITH CLEFT PALATE (CL) AND UNILATERAL CLEFT LIP, PALATE AND ALVEOLUS (UCLPA)-A COMPARATIVE STUDY.

Background:To evaluate and compare the oral hygiene and periodontal status in children with cleft palate (CP) and unilateral cleft lip, palate and alveolus. Method: 60 patients were taken for the study. They were divided...

SEGMENTATION OF LOAD GROUPS ON A SINGLE PHASE KWH-METER USING THE PAYLOAD DATA HANDLING SYSTEM.

A minimum system that controlled by microcontroller has been established for load groups segmentation on a single-phase kWH-meter using the payload data handling system. Minimum system that controlled by microcontroller...

LAND USE AND RECOGNİTİON OF CONSTRUCTİON TECHNİQUES BASED ON LAND USE AND GEOGRAPHİCAL CLİMATİC CONDİTİONS.

Technology controls our lives in a very high way and thus reflected on architecture, it leads us to two pints, first, gradually we stay away from the architectural identity in some countries like in Egypt, Sec. The price...

LINKING EFFECTIVE PROFESSIONAL DEVELOPMENT AND ELEMENTARY MATHEMATICS INSTRUCTION.

This study examined teachers? perceptions of the effectiveness of a hands-on workshop focused on mathematics instructions in a literacy-focused environment. The research institute was provided funding from the Teacher Qu...

Download PDF file
  • EP ID EP401013
  • DOI 10.21474/IJAR01/7769
  • Views 67
  • Downloads 0

How To Cite

Sarah Mahmoud Abdabagi, Fayhaa Mohammed Altayeb, Ahmed BakheetAbdAlla, RaniaAbdAlrhaman Osman, Ali ElaminNasir. (2018). EVALUATION THE EFFECT OF THE MALARIA PARASITE ON PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME LEVELS AMONG SUDANESE PATIENT IN KHARTOUM STATE- SUDAN.. International Journal of Advanced Research (IJAR), 6(9), 1045-1049. https://europub.co.uk/articles/-A-401013