Events following BCG vaccination during neonatal period and factors that might affect potency and side effects
Journal Title: Journal of Vaccines & Immunization - Year 2013, Vol 1, Issue 1
Abstract
Introduction: In Sri Lanka, BCG vaccine is given during neonatal period. There are many myths regarding BCG vaccine and sequelae of vaccination are not clearly documented in medical literature. Objectives: Objectives of this study were to describe the sequelae of BCG vaccination and to find out the scientific basis of beliefs related to it. Methods: A prospective observational study was carried out at Ragama teaching hospital and two private hospitals in Gampaha district. 125 babies each from government and private sector were recruited, with consent from parents. Vaccine was administered by a consultant Paediatrician. Vaccine site was cleaned with 70 % alcohol and allowed to dry before vaccination. All babies were bathed on same day. Babies were followed up until a scar was detected. Results: Only 182 babies completed the follow up and all babies developed a scar. Time taken for a reaction varied, but all babies had a reaction by 8 weeks and a scar by 14 weeks. None had fever or other adverse reactions attributable to the vaccine. Conclusions: Cleaning the vaccination site with alcohol, bathing and time of vaccination has no influence on side effects or efficacy of the vaccine. BCG is a safe vaccine provided correct technique of administration is employed.
Authors and Affiliations
Perera PJ, Ranathunga N, Samaranayake GB
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