Evidence-Based Tropical phytotherapeutic Treatment Protocol For Lumbar slipped Disc: An Approach With Biochemical, Anatomical, Functional Disability and Radiological parameters
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
Introduction: Lumber slipped disc (LSD) attributes to a problem with an intervertebral disc of the lumber spine, whereby a gel-like material (nucleus-pulposus) inside the disc that protrudes through a crack in the outer-wall (annulus-fibrosus) of the disc and compressed a nearby nerve root causes inflammation, pain, numbness or weakness in the leg that lead to abnormal quality of life. The aim of the study is to normalize the LSD with the aberrant levels of Interleukin-10 (IL-10), Tumor necrosis factor-alpha (TNF-α), Creatine kinase-muscle (CKMM) and AldolaseA (AldoA)along with anomalous anatomical and international acclaimed functional disability parameters and radiological images by topical phytotherapeutic treatment protocol within six-week. Methods: Baseline data were collected and evaluated from 108 patients, aged 58.60±9.94 years, suffering with LSD for 4.68±2.22years. Serum IL-10, TNF-α, CK-MM and AldoA levels were measured for all the patients at the baseline and post-treatment using appropriate kits. All patients underwent standardized physical, radiographic examinations, and completed a questionnaire. Results: The abnormal levels of above-mentioned biomarkers during LSD were recorded as their mean±SD values, 16.06±1.98pg/ml, 12.54±0.95pg/ml,106.89±30.06U/L, and 5.28±1.13U/L respectively at post-treatment and all were highly significant(p<0.0001). The improvements on deranged anatomical features, internationalapproved functional disability parameters and reduction of over-weight under VAS, KPS, LEFS, ODI, and BMI were all highly significant(p<0.0001) and radiological images under KL scale at post-treatment when compared to the baseline. Conclusions: It is firmly concluded that LSD resulted in the anomalous levels of above-mentioned biomarkers along with the aforesaid aberrant parameters can be successfully normalized by topical phytotherapeutic treatment protocol within six-week.
Authors and Affiliations
Apurba Ganguly, Devika Ganguly
Keywords
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