Ewing’s Sarcoma of Right Lung in a 32 Years Old Male Patient
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 3
Abstract
Ewing’s sarcoma is the second most common primary osseous malignancy in children and young adults.However, infrequently, it can arise outside the skeletal system; rarer still, it can originate within the lung parenchyma. Thirty two year old male patient who presented with three months history of cough and gradual onset respiratory distress followed by pain and heaviness of right hemithorax. 0n imaging revealed right sided mid lobe mass and pleural effusion. Trucut biopsy from the lung lesion showed small, blue, round or ovoid cells. Immunohistochemistry was done to establish the diagnosis. It reveals the cells positive TTF1, Calretinin. The Ki-67 labelling index is about 95%. The overall picture is for CD99, FLI1, CD 56 (focal) and negative for Chromogranin, Desmin, S100 , EMA, compatible with PNET/ Ewing’s sarcoma. With diagnosis of Ewing’s sarcoma, VAC (Vincristine, Adriamycin, Cyclophosphamide) alternating with IE (Ifosfamide, Etoposide) chemotherapy regimen was started. Patient completed 17 cycles of chemotherapy the disease is clinically and Radiologically responding. Patient was sent to cardiothoracic department for surgical opinion. Patient underwent surgical resection followed by radiotherapy and now doing well at 2 months follow-up.
Authors and Affiliations
Swapan Kr Mallick Mallick
Keywords
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