Expanding the Classification of Leukemia by the World Health Organization over Time
Journal Title: Haematology International Journal - Year 2019, Vol 3, Issue 1
Abstract
The classification has always been the basis for many treatments of the disease. The French-American-British has performed leukemia classification base on morphological finding, but the World Health Organization apply gene or chromosomal mutations in its classification. This approach has revolutionized the diagnosis, choose strategy of treatment and follow-up ever since. Although WHO has classified leukemia on the basis of FAB; but genetic mutations has made the wider and more specific outcome. Obviously, identifying these damages provide an extensive filed for researchers and physicians to effective assistance for patients. Therefore, the purpose of this review is comparing revisions of WHO classification in the years 2008 and 2016, because these categories are highlighted unknown cases that give researchers incentives to further study.
Authors and Affiliations
Gholamhossein Tamaddon
Keywords
Related Articles
- EP ID EP591334
- DOI 10.23880/hij-16000138
- Views 106
- Downloads 0
Peripheral T Cell Lymphoma with Follicular Helper Phenotype, Case Report and Literature Review
T-cell lymphomas are a heterogeneous group of lymphoid neoplasms, with a broad classification; in which the peripheral T-cell lymphoma not otherwise specified, is the most frequently diagnosed subtype, demonstrating the...
Fatal Case of Haemophagocytic Syndrome Associated With Infection of Plasmodium Falciparum
Haemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory condition which can occur as a primary syndrome (genetic in origin) or arise secondary to infectious, rheumatologic, malignant or metabolic disorders. HLH...
Environmental Factors as Determinants of Severity of SCD in Nigeria
Sickle cell anaemia (SCA) is a chronic blood disorder characterized by red blood cells that assume an abnormal sickle shape when deoxygenated and may block different areas of the microcirculation causing ischaemia in var...
Impairment of Micronucleus and DNA in the 2-Chloro-4-Ethylamino-6- Isopropylamino-1, 3, 5-Triazine Exposed Poecilia Sphenops
The micronucleus and DNA fragmentation assays have been used progressively more to evaluate genotoxicity of many compounds in contaminated aquatic atmosphere. The objective of the current study was to investigate the gen...
Long-lasting Responses to Immunomodulatory Drugs (IMIDs) in Combination with Dexamethasone in Multiple Myeloma; Identification of Exceptional Responders at any Treatment Line
1.1. Background: There is a growing interest in the study of patients that achieve exceptionally long-lasting remissions although suffering from incurable neoplastic disorders. This is the case for multiple myeloma (MM),...