Experimental Evaluation of Anti Convulsant Property of Myristica Fragrans
Journal Title: Journal of Chalmeda AnandRao Institute of Medical Sciences - Year 2018, Vol 16, Issue 2
Abstract
Background: Myristica fragrans (Nutmeg) has been traditionally known since ancient days for its nutritive and various effects in the body. In traditional medicine, Myristica had been used for its digestant, carminative and anti-ulcer property, as an analgesic, antiinflammatory, anti-convulsant and many more. Aim: The aim of the present study is evaluation of anticonvulsant property of extract of Myristica fragrans in albino rats. Materials and Methods: Five groups consisting of six rats each were taken, Gr1 served as control, Gr 2 as standard, given phenobarbitone, Gr 3, 4 and 5 were test groups with various doses of Myristica extract. The convulsions were induced by Pentylenetetrazole. The effects anticonvulsant effects of Myristica are compared with standard anticonvulsant Phenobarbitone. Result: Myristica fragrans extract showed statistically significant anticonvulsant property in test group. Conclusion: Myristica fragrans extract has to be tested with other species and electricallyinduced convulsions also.
Authors and Affiliations
Sam Pavan Kumar G, Laxmipathi Kodam, Pushpalatha Chinnam
Keywords
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