Experimental remodeling of vascular bed tissue for combined expanded perforator-based flaps obtaining

Apply

Experimental remodeling of vascular bed tissue for combined expanded perforator-based flaps obtaining

Journal Title: Хірургія України - Year 2018, Vol 0, Issue 1

Abstract

The aim — to study the effect of expansion on the vascular bed tissues remodeling to obtain the combined perforator-based flaps and to determine their survival in the experiment. Materials and methods. Experimental studies were carried out on 35 rats, which underwent the skin flaps modelling supplied with skin perforators of the thoracic artery and superior gluteal artery. In the main group (n = 20), the expanded combined flaps with vascular networks of the posterior and middle muscle perforators of VII—X intercostal and I — II lumbar arteries and lateral artery of the chest were formed. The comparison group included 15 rats, in whom flaps with different power sources were formed on one side of the trunk. A comparative analysis of flap survival for different flap formation methods, including tissue expansion, was held. Results and discussion. The possibility of vascular bed remodeling, which allows the large expanded flaps formation which unite up to 5 perforasome skin areas supplied by single key vessel, is shown. Today, there is no universal method to improve the survival of the skin flaps, so tissue expansion with the inclusion of the neighboring 5 vascular sources perforators will help to obtain more plastic material with better survival potential. Conclusions. Tissue expansion facilitates the inclusion of additional vascular networks into the flaps, the vascular bed remodeling, allows to increase the flaps square in 1.9 times, improves their survival in 2.4 times and reduces the necrosis square in 2.8 times.

Authors and Affiliations

O. A. Zhernov, G. P. Kozinets, M. Kitri, O. O. Huz

Keywords

Acute carcinomatous pancreatitis in patients with pancreatic head cancer complicated by obstructive jaundice

The aim — to improve the diagnostic and surgical palliative treatment results in patients with unresectable pancreatic head cancer, complicated by obstructive jaundice with the canceromatous pancreatitis. Materials and...

Pathomorphological and cytological control of the pancreatic remnant and main pancreatic duct during radical operations in patients with pancreatic adenocarcinoma

The aim — to determine the diagnostic and predictive value of intraoperative study of pancreatic remnant during radical operations in patients with ductal adenocarcinoma of the pancreas. To investigate the role and place...

EP ID EP279677
DOI -
Views 148
Downloads 0