Experimental Schizophrenia Models

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Experimental Schizophrenia Models

Journal Title: Kocaeli Üniversitesi Sağlık Bilimleri Dergisi - Year 2015, Vol 1, Issue 1

Abstract

Schizophrenia is a unique disease which cannot be mimicked exactly in experimental animals. In experimental animals, the thoughts cannot be explained by talking like in men and this causes it difficult to form a sufficient schizophrenia model in experimental investigations. However, some models were used to investigate the effects of new drugs in the therapy of schizophrenia and in the physiopathology of schizophrenia. Some of these models can be classified as locomotion and stereotype models, conditioned avoidance responding, catalepsy test, rat paw test, selfstimulation paradigms, prepulse inhibition of the startle reflex, latent inhibition paradigms, evaluating schizophrenia by social interaction test in rodents, cognitive models, cellular and molecular models, pharmacological models, developmental models, genetic models.

Authors and Affiliations

Oğuz Mutlu, Havva Kaya

Keywords

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EP ID EP45021
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