Exploration of the relationship between the storage time of leukodepleted red blood cell and transfusion adverse reactions
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 10
Abstract
Objective To explore the relationship between the storage time of leukodepleted red blood cells and transfusion adverse reactions by analyzing the occurrence of transfusion adverse reactions of patients after leukodepleted red blood cells transfusion from four hospitals. Methods By using the electronic medical record management system, the collection and transfusion dates of leukodepleted red blood cells from four hospitals in Enshi Prefecture from 2018 to 2022, as well as the information on transfusion adverse reactions, were retrieved. Results From 2018 to 2022, a total of 697 61 bags of leukodepleted red blood cells were transfused in four hospitals, resulting in 166 cases of transfusion adverse reactions, among which 93 were allergic reactions, 63 were non hemolytic febrile reactions, and 10 were others, with a total incidence rate of transfusion adverse reactions at 0.24%. The average storage time of leukodepleted red blood cells with and without transfusion adverse reactions was (20.25±6.31) and (19.88±5.50) days, respectively. With a storage time of 7 days as the threshold, the incidence of transfusion adverse reactions was the lowest for a storage time of 15~21 days. The incidence of transfusion adverse reactions of leukodepleted red blood cells in two groups (with storage days ≤21 days and >21 days) was not statistically significant(P>0.05). Conclusion Allergic reactions were the main type of transfusion adverse reaction caused by leukodepleted red blood cells, and the incidence of transfusion adverse reactions decreased and then increased with the prolongation of the storage time of leukodepleted red blood cells. There was no significant difference in the incidence of transfusion adverse reactions with leukodepleted red blood cells stored for ≤ 21 days and >21 days.
Authors and Affiliations
Liu HE, Jian LIU, Gang WU, En WANG, Fayan YI, Xingshun TAN, Shiyu ZHU, Rui YU, Guanghui LU, Yan LIU, Mei ZHAI, Qing XIANG, Ping LIU, Yanhua LIAO, Zhizhen FU, Maolin LI, Rong HUANG
Keywords
Related Articles
- EP ID EP738659
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.10.008
- Views 45
- Downloads 0
Occult hepatitis C virus infection in volunteer blood donors in Shaanxi province
Objective To investigate the prevalence of occult hepatitis C virus infection (OCI) in Shaanxi blood donors and characterize the occult hepatitis C virus in this cohort. Methods Between July and September of 2019, 112, 1...
Hepatitis E virus prevalence among blood donors in Wuhan
Objective To investigate the prevalence and risk factor of hepatitis E virus(HEV) infection among blood donors in Wuhan. Methods A total of 1 302 serum samples (including 1 076 with normal ALT and 226 with elevated ALT)...
Study on the confirmation of treponema pallidum antibody reactivity in blood donors
Objective To evaluate the feasibility of confirming syphilis reactive blood donors. Methods The serum of donors with anti-TP reaction by ELISA were confirmed by treponema pallidum particle agglutination (TPPA) and Wester...
Informationization and development strategy in blood collection and supply institutions in Beijing
[Objective] To investigate and analyze the current status, needs and issues of information system construction in blood collection and supply institutions in Beijing, and to provide strategic suggestions for the further...
Characteristics of whole blood donors from 26 blood stations before and after the outbreak of COVID-19:a multicenter study
Objective To analyze the basic characteristics of whole blood donors from blood stations before and after the outbreak of COVID-19. Methods After excluding invalid data, data related to the basic characteristics of whole...