Exploring Metformin as the Potential Oral Antidiabetic of Choice for Type II Diabetes Mellitus with Wound Comorbid: A Case-based Literature Review
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2023, Vol 3, Issue 3
Abstract
Diabetes is a metabolic disease characterized by hyperglycemia caused by a disruption in insulin secretion, insulin function, or both. An individual with diabetes have a greater likelihood to develop chronic non-healing wounds, and if untreated, various chronic complications are associated with psychiatric stress and depression. In diabetic wounds, the inflammatory phase becomes persistent and excessive with impaired cell proliferation and greater risk of infection. Several studies have shown that metformin has potential effect for diabetic wound healing. Here, we reported a case of diabetic wound in East Jangkat, a rural area in Indonesia, with premorbid type 2 diabetes mellitus and obesity class II with a deeper discussion about the potential effect of metformin for wound healing in diabetic ulcers.
Authors and Affiliations
Almira Talitha Ulima, Ahmad Fawzy
Keywords
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- EP ID EP739884
- DOI 10.47191/ijmscrs/v3-i3-38
- Views 38
- Downloads 0
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