EXPOSURE TO UPPERCOTT AFFECTS HEMATOLOGICAL INDICES IN MALE ALBINO WISTAR RATS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 9
Abstract
The hematological indices of Albino rats treated with uppercott at 2.5%, 5% and 7.5% of LD50 were assessed. Forty-five male albino rats, divided into 5 groups of nine rats each were used. Group 1 (control) was fed rat chow only; group 2 was used as the vehicle (Control administered only oil); while groups 3-5 (experimental groups) were treated with uppercott at different concentrations. The results as compared to the control groups showed that WBC concentration was significantly higher (p<0.05) in 5%M compared to OCM and other test groups. RBCs were not significantly decreased across all test groups. HGB was slightly decreased in 7.5% M compared to all controls and test groups, while HCT significantly increased in 5%M. No significant difference was observed in the MCV concentration, whereas, MCH and MCHC significantly decreased (p<0.05) in 7.5%M compared to all controls and test groups. Platelets concentration significantly (p<0.05) increased in OCM compared to NCM and other test groups. Lymphocytes decreased significantly (p<0.05) in 7.5%M compared to control and other test groups. Over all data showed that uppercott had a deliterous effect on hematological indices suggesting that uppercott is an environmental pollutant, which should be used with caution.
Authors and Affiliations
Dr. Modo Emmanuel U.
Keywords
Related Articles
- EP ID EP630785
- DOI -
- Views 159
- Downloads 0
A CASE STUDY AND CLINICAL LITERATURE REVIEW OF FOURNIER’S GANGRENE, DEMONSTRATING RESOLUTION WITH ANTIBIOTIC THERAPY AND IN THE ABSENCE OF SURGICAL OR ANY OTHER INTERVENTION
This case report describes a lesser common condition, namely Fournier's gangrene, involving a rapidly advancing, necrotising infection of deep tissues, starting from the perineal area with spread along fascial planes. Th...
PRODUCTION OF ESSENTIAL OIL AND CONCRET IN VARIOUS TYPES OF TOBACCO (NICOTIANA TABACUM L.)
The essential oils in tobacco are used as a key ingredient for keeping the taste and aroma. The pleasant smell in tobacco leafs comes from the essential oils and polyphenols. The positive correlation between the producti...
SERO-PREVALENCE OF HEPATITIS C VIRUS INFECTIONS AMONG BLOOD DONORS AND CLINICAL VISITORS IN AMRAN GOVERNORATE,YEMEN
Hepatitis C virus is identified as a member of the RNA Flaviviridae that can cause acute and chronic infections in human. So, the present study was conducted in Amran general hospital, Amran city, Yemen, eight hundred (8...
THE EFFECT OF ANTIOXIDANT ACTIVITY, CYTOTOXICITY, AND INFLAMMATORY CYTOKINE PRODUCTION OF ELEVEN ESSENTIAL OILS
Essential oils are complex mixtures of several components endowed with a wide range of biological activities. The objectives of this study were to chemically characterize and evaluate the antioxidant activity, cytotoxici...
AN ASSESSMENT OF QUALITY OF LIFE IN LIBYAN PATIENTS UNDERGOING HEMODIALYSIS
Background: In patients with end-stage renal disease, the need for renal replacement therapy to prolong life represents the final stage of living. Quality of life is one of the concepts that was accepted as a criterion f...