Expression of Podoplanin in Odontogenic Keratocyst: An Immunohistochemical Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 3
Abstract
Background: The odontogenic keratocyst (OKC) is known to have a more aggressive biologic behaviour than other cysts of jaw. Podoplanin which is frequently used as a lymphatic endothelial marker in OSCCs has recently been found to play a possible role in odontogenic tumorigenesis also. Hence; we planned the present study to assess the role of podoplanin in OKC. Materials & methods: The present study included evaluation a total of 20 OKC specimens and 20 dental follicle specimens (Control). The tissue sections were stained; one with hematoxylin and eosin (H & E) stain and another with Podoplanin Antihuman antibody by immunohistochemical methods. All the results were analyzed by SPSS software. Results: Significant results were obtained while comparing the mean staining final score in between OKCs specimens and dental follicle specimens. Conclusion: Podoplanin influences the proliferative activity of basal and suprabasal cells in the epithelial lining of OKCs. However; future studies are recommended.
Authors and Affiliations
Jasmin Singh, Sanjeet Singh
Keywords
Related Articles
- EP ID EP505721
- DOI -
- Views 125
- Downloads 0
Case Report of Trichoepithelioma over Eyelid
Solitary trichoepithelioma of the eyelid is a very rare tumor, which needs to be differentiated from basal cell carcinoma. Diagnosis is based on clinical and histopathological examination. We present a case of a solitary...
Antimicrobial Effect of Cow Urine and Goat Urine against common Dental Caries Pathogens: An in vitro Comparative Study
Background- The emergence of resistant bacterial strains due to overuse of antibiotics has led to increase in use of natural animal products with known antimicrobial properties as therapeutic agents. Objectives- To asses...
Assessment of Recurrent Aphthous Ulcers in Study Population
Background: Recurrent aphthous stomatitis (RAS) is a type of recurrent ulcer where it heals and reappears after a period of time. The present study was conducted to assess the cases of RAS in study population. Materials...
Correlation of the Effectiveness of an Herbal Mouth Rinse with a Chlorhexidine Mouth Rinse: An Original Study
Introduction: Mouthwashes are an accompaniment to, not a replacement for, standard brushing strokes and flossing. Chlorohexidine is a bis-biguanide that is both hostile to plaque and antibacterial properties. It has symp...
Evaluation of Complications in Uterus Surgery- A Clinical Study
Background: Worldwide hysterectomy is the most commonly performed major gynecological surgical procedure. The present study was conducted to assess the complications of uterus surgery. Materials & Methods: The present st...