Extrapancreatic Infections in Acute Pancreatitis and its Influence on Disease Outcome
Journal Title: National Journal of Medical Research - Year 2017, Vol 7, Issue 1
Abstract
Introduction: Limited data is available on prevalence of extrapancreatic infection, its influence on outcome of pancreatitis. Objectives: To assess the prevalence of extra-pancreatic infections in acute pancreatitis, identify risk factors for development of such infections and influence of extrapancreatic infections on outcome of pancreatitis. Methodology: Patients of acute pancreatitis admitted from June 2013 to July 2015 were recruited in the study. The patients who developed extra-pancreatic infection formed the study group while patients who didn’t develop infections were included in the control group. Both groups were followed and their final outcome was compared. Results: A total of 350 patients comprising of 158 cases and 192 controls were studied. Prevalence of extra pancreatic infections was found in 41.5% with Urinary tract infections (UTI)(14.4 followed by Biliary (10.0%), pulmonary (8.4%), Pulmonary and UTI (3.7%),Injection site infections (2.1%). Predisposing factors for development of extra pancreatic infections and subsequent outcome of acute pancreatitis was found to be influenced by duration of hospital stay (p<0.001), etiology of acute pancreatitis and comorbidities especially Diabeties mellitus (p<0.001). Conclusions: Early detection and proper treatment of infections will definitely improve outcome of acute pancreatitis with infections.
Authors and Affiliations
Majid Abbas Khawaja, Reyaz Ahmed Para, Mushtaq Ahmad Khan, Adnan Firdous Raina, Sumera Saba
Keywords
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