Eye for IgG4-Related Disease
Journal Title: Clinical Medical Image Library - Year 2017, Vol 3, Issue 2
Abstract
IgG4-related disease is a relatively new disease which has gained significant recognition in the last decade. It is an immune mediated disease and diagnosis is often missed because of limited awareness and a typical presentation. The diagnosis of IgG4-related disease is confirmed by a characteristic histopathological appearance in any organ site, comprising of lymphoplasmacytic infiltrate, storiform fibrosis and obliterative phlebitis with elevated IgG4-positive plasma cells. Early detection is crucial to prevent organ damage as they are usually responsive to glucocorticoids and immunomodulatory therapy.
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