Factors Affecting Hypocalcemia in Patients Undergoing Bilateral Total Thyroidectomy
Journal Title: The Medical Bulletin of Haseki - Year 2019, Vol 57, Issue 3
Abstract
Aim: Bilateral total thyroidectomy is performed for the treatment of multinodular goiter, thyroid cancer and hyperthyroidism. Hypocalcemia is the most common complication seen after operation and may be transient or permanent. The aim of our study was to reveal the factors associated with hypocalcemia after surgery and measures that can be taken for the prevention of hypocalcemia. Methods: We retrospectively evaluated records of patients who underwent total thyroidectomy between January 2013 and September 2017 in our clinic. Demographic characteristics, thyroid hormone and vitamin D levels, calcium and parathyroid hormone levels before and after surgery, oral or intravenous calcium replacement requirements and length of hospital stay were recorded. Patients who underwent neck dissection and completion surgery and who were operated for hyperthyroidism were excluded. Results: A total of 721 patients (576 female and 145 male) were included in the study. The mean postoperative calcium level in females and males was 8.1±0.7 mg/dL and 8.5±0.4 mg/dL, respectively (p=0.001). The mean preoperative vitamin D level in females and males was 13.7±7.3 ng/mL and 8.5±0.4 ng/mL, respectively (p<0.001). The mean postoperative parathyroid hormone level in females and males was 30.7±15 ng/L and 34.8±14.5 ng/L, respectively (p=NS). The mean postoperative parathyroid hormone level and length of hospital stay in hypocalcemic and normocalcemic patients was 37.1±12.5 ng/L and 27.9±15.3 ng/L (p<0.001) and 2.58±1.23 and 2.08±0.5 days, respectively (p=0.001). Conclusion: Vitamin D insufficiency, postoperative hypoparathyroidism and female sex were found to be risk factors for postoperative hypocalcemia. Among these risk factors, vitamin D insufficiency can be treated before surgery to prevent this complication.
Authors and Affiliations
Sercan Yüksel, Ekrem Ferlengez, Gamze Çıtlak
Keywords
Related Articles
- EP ID EP50763
- DOI 10.4274/haseki.galenos.2018.4936
- Views 265
- Downloads 0
Do Inner Ear and Mastoid Bone Structural Variations Have a Determining Role on Vestibular Symptoms of Migraine?
Aim: To investigate the possible relationship between morphological changes caused by anatomical structural differences and functional impairment in Vestibular migraine (VM) and Chronic Migraine (CM) disease. Methods: A...
Clinical and Radiological Early Results of Acetabulum Fractures Operated with the Modified Stoppa Approach
Aim: To evaluate the follow-up results of patients hospitalized for acetabular fractures and treated with the modified Stoppa approach. Methods: Records of fifty-two Acetabula from 48 patients who were followed up for a...
Synchronous Bilateral Male Breast Cancer: A Rare Case Report
Male breast cancer accounts for less than 1% of all breast carcinomas and 0.17 to -1.5% of all cancers seen in men. The incidence of synchronous bilateral male breast cancer has been reported to be 1.5%-2% of all male br...
Blockade of the Neprilysin and Angiotensin Ameliorates Oxidative Stress in the Cardiovascular Target Tissues of Dexamethasone-induced Hypertensive Rats
Aim: The imbalance between production of reactive oxygen species and antioxidant defense determines the degree of oxidative toxicity and severity of subsequent myocardial damage.We aimed to evaluate the anti-oxidative ef...
Risk Factors Triggering the Development of Preeclampsia in Pregnant Women with Isolated Gestational Proteinuria and Perinatal Outcomes
Aim: To determine the risk factors for preeclampsia in isolated gestational proteinuria and to compare perinatal outcomes between women who did and did not develop preeclampsia. Methods: Seventy-six pregnants, who were...