Factors Affecting Outcomes of IVF in Unexplained Infertility
Journal Title: Saudi Journal of Medicine - Year 2018, Vol 3, Issue 12
Abstract
Unexplained infertility refers to the absence of a definable cause for infertility despite a thorough evaluation. Subtle abnormalities like mild endometriosis, minor tubal dysfunction as evidenced by presence of peritubal adhesions or partial fimbrial phimosis, endometrial defects, may be unearthed by thorough investigations in these couples labelled with unexplained infertility. Primary objective of the study was to determine if IVF outcomes in unexplained infertility are different from other cause of infertility like male or tubal factor infertility. Secondary objectives were to find out what intrinsic or extrinsic factors in unexplained infertility influence IVF results. Based upon these factors, to help in prognosticating couples with unexplained infertility before they enter IVF. The study was explained to all eligible couples undergoing IVF at centre. They were offered participation in study and given a patient information sheet to understand the study. Those who accepted to take part in the study were enrolled in study. After applying inclusion and exclusion criteria, three cohorts of unexplained, male and tubal are formed according to their indication of IVF cycle. Age of female partner was the only variable which showed statistically difference. Mean age of female partner of unexplained group was 34.12 ± 3.69 years, and of tubal & male group it was 33.00 ± 4.2years 3, 32.13 ± 3.69 years respectively (p value 0.047 < 0.05). Laparoscopy and hysteroscopy offered not only to establish the diagnosis but also helping couple knowing their chances of successful pregnancy in IVF.
Authors and Affiliations
Dr. Sunita Saharan, Dr. Ruma Satwik, Dr. Abha Majumdaar
Keywords
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