Factors influencing hemolysis rate of leukocyte-reduced red blood cells at the end of preservation period in blood donors
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 12
Abstract
Objective To compare the current standards and explore the influencing factors for hemolysis rate of leukocyte-reduced red blood cells at the end of the preservation period, in order to formulate reasonable internal control indicators. Methods A retrospective analysis was performed on hemolysis rate of 427 samples of leukocyte-reduced red blood cells at the end of the preservation period in Nanning Blood Center from 2015 to 2022. Compared with the current standard for hemolysis rate at the end of the preservation period (GB 18469-2012 Quality Requirements for Whole Blood and Component Blood), the differences were analyzed, and the factors influncing the hemolysis rate were analyzed in terms of different blood donor groups. Results 1) Among the 427 samples, the hemolysis rate of 418 (97.89%) did not exceed 0.4%, all lower than 0.8%; 2)the hemolysis rate of the male group was higher than that of the female group; 3) the hemolysis rate of the 18-29 years old group was lower than that of the 30-39 year old group and the 40-60 year old group, with statistically significant difference; 4) in terms of occupation, the hemolysis rate of students was the lowest, and the differences between groups were statistically significant; 5) no statistical significance was found in ethnicity and blood type. Conclusion Statistics indicated that gender, age, blood donation volume and occupation of blood donors were the influencing factors of hemolysis rate. The current standard is obviously higher in the qualified range of blood quality control in Nanning. It is advisable to formulate a reasonable quality control strategy with internal control index of hemolysis rate set <0.4%, which is conducive to making accurate evaluation of internal quality control and ensuring blood safety.
Authors and Affiliations
Liujuan ZHANG, Xinwei WANG, Dong PANG, Yangchun PAN, Zhenxing WEI, Xiong LI, Qiuting ZHU, Ruru HE, Hui ZHANG
Keywords
Related Articles
- EP ID EP738725
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.12.016
- Views 29
- Downloads 0
Overview on haemovigilance about delayed transfusions in the UK and blood shortage in the USA
Serious hazards of transfusion(SHOT)in the United Kingdom has been received reporting of the adverse events of delayed transfusion for more than ten years. Hemovigilance Module Surveillance Protocol in Biovigilance Compo...
Research progress on platelet rich plasma in management of patients with knee osteoarthritis
Knee osteoarthritis (KOA) is a common chronic degenerative disease of cartilage, which often occurs in middle-aged and elderly patients. It can cause joint swelling, pain and limited movement. With the aging population g...
Ambiguous blood matching caused by multiple blood transfusions resulting in anti-C, anti-JKb combined with Anti-Wra: a case report
Objective To study the reasons for ambiguous blood matching in a patient who received multiple blood transfusions, and explore how to reduce the risk of producing homologous antibodies in patients who received multiple b...
Analysis and evaluation of hepatitis B test results of blood nucleic acid testing under different screening modes
Objective To evaluate the effectiveness of Roche Cobas s 201 in detecting HBV by analyzing its blood nucleic acid testing (NAT) results. Methods The results were grouped according to the enzyme-linked immunosorbent assay...
Diagnosis and treatment of passenger lymphocyte syndrome following secondary ABO-incompatible allogeneic hematopoietic stem cell transplantation
Objective To investigate the clinical characteristics and diagnosis and treatment of passenger lymphocyte syndrome (PLS) in patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods A tot...