FDG PET/CT Imaging for Evaluation of Treatment Response in Lung Cancer
Journal Title: Nükleer Tıp Seminerleri - Year 2018, Vol 4, Issue 1
Abstract
Lung cancer is the most common cause of cancer-related mortality worldwide. Surgery, radiation therapy, systemic chemotherapy, and biological therapy are the modalities used to treat lung cancer. Despite recognized limitations, structural imaging with computed tomography (CT) remains the standard technique for evaluating the response of lung cancer to both chemotherapy and radiotherapy. Metabolic imaging with positron emission tomography/computed tomography (PET/CT) using F-18 fluoro-2-deoxy-glucose (FDG) shows difference in monitoring the tumor response to therapy by integrating anatomic and functional measures of treatment effects. The high uptake of F-18 FDG in most lung cancers and the demonstration that successful treatment reduces uptake have led to increasing enthusiasm for the use of PET/CT to assess the therapeutic response. In this review, theoretic considerations and current evidence supporting the role of F-18 FDG PET/CT for evaluation of treatment response in lung cancer are discussed.
Authors and Affiliations
İnanç Karapolat
Keywords
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- EP ID EP274195
- DOI 10.4274/nts.2018.007
- Views 99
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