Features of Atopic Reactivity in Schoolchildren with Severe Bronchial Asthma
Journal Title: Здоров`я дитини - Year 2014, Vol 8, Issue 59
Abstract
The study involved 30 students with severe bronchial asthma and 30 children with moderate to severe course. Patients with severe bronchial asthma revealed a clear tendency to increase the relative content of interleukin 4 in peripheral blood, which indirectly indicates the severity of inflammation in the bronchi. Almost every second child suffering from severe bronchial asthma reported an increase in the concentration of immunoglobulin E (more than 545.3 IU/ml), and the odds ratio was 1.9 (95% CI 1.1–3.4). In the group of patients with severe bronchial asthma, cases of increased skin sensitivity to household allergens were significantly more frequent compared to the second group. Thus, the size of hyperemia over 15.0 mm was recorded in 81.5 % of children of the first group and only in 51.9 % of persons (Pϕ < 0.05) in the second one. Clinical and epidemiological risk and diagnostic value of individual indicators of atopic reactivity were determined to verify the phenotype of severe bronchial asthma.
Authors and Affiliations
U. I. Marusyk
Keywords
Related Articles
- EP ID EP320236
- DOI -
- Views 113
- Downloads 0
Value of Bacterial Lysates in Prevention of Acute Respiratory Infections in Children
The problem of acute respiratory infectious and inflammatory diseases in children is considered in the article. The functions of nonspecific defense system are described, and there is also given a detailed description of...
Vitamin and Mineral Supplementation of Children under Current Conditions
This paper presents data about the state of vitamin and trace-element supplementation of children from different countries and Ukraine. It was shown that nutrition does not fully satisfy the need for vitamins and trace e...
Correlation between Bronchovascular and Cardiovascular Disorders in Children with Bronchial Asthma: Multifacetedness and Inexhaustibility of Problem Study
Due to tight functional interrelation between respiratory apparatus and blood circulation, exacerbation of bronchial asthma in children is associated with changes of cardiovascular system. Multifacetedness of this proble...
Pharmacological effect on biofilm dispersion. Derivatives of the diffusible signal factor family
The scientific review deals with the role of representatives of the family of the diffusible signal factor (DSF), which are cis-2-decenoic acid, in the process of dispersing biofilms of pathogenic bacteria. For writing t...
Development of the immune response in pneumonia induced by Staphylococcus aureus (part 3)
The article analyzes the key role of pro-inflammatory and anti-inflammatory cytokines in the development of immune response in pneumonia caused by Staphylococcus aureus based on the literature data. Genes associated with...