Features of Atopic Reactivity in Schoolchildren with Severe Bronchial Asthma
Journal Title: Здоров`я дитини - Year 2014, Vol 8, Issue 59
Abstract
The study involved 30 students with severe bronchial asthma and 30 children with moderate to severe course. Patients with severe bronchial asthma revealed a clear tendency to increase the relative content of interleukin 4 in peripheral blood, which indirectly indicates the severity of inflammation in the bronchi. Almost every second child suffering from severe bronchial asthma reported an increase in the concentration of immunoglobulin E (more than 545.3 IU/ml), and the odds ratio was 1.9 (95% CI 1.1–3.4). In the group of patients with severe bronchial asthma, cases of increased skin sensitivity to household allergens were significantly more frequent compared to the second group. Thus, the size of hyperemia over 15.0 mm was recorded in 81.5 % of children of the first group and only in 51.9 % of persons (Pϕ < 0.05) in the second one. Clinical and epidemiological risk and diagnostic value of individual indicators of atopic reactivity were determined to verify the phenotype of severe bronchial asthma.
Authors and Affiliations
U. I. Marusyk
Keywords
Related Articles
- EP ID EP320236
- DOI -
- Views 96
- Downloads 0
Premorbid disorders of pancreatic functional state in children with chronic gastroduodenal pathology
Background. Secondary pancreatic insufficiency in pediatric practice happens increasingly frequently and can occur at any age, both against the background of nutritional deficiencies, and various inflammatory diseases of...
Conservative Approach Efficacy in Closed Injuries of Parenchymal Abdominal Cavity Organs in Children
This article summarizes the experience of the conservative approach application in closed injuries of parenchymal organs of the abdominal cavity in children. In our clinic 53 patients with closed injuries of the spleen a...
Modern problems of treatment of Helicobacter-associated diseases in children: opportunities of adjuvant therapy
Background. The relevance of research is related to a significant spread of the pathology of the upper digestive tract in children, which in most cases is caused by the pathogenic effect of Helicobacter pylori (Hp). Mode...
Hereditary Angioedema
Hereditary angioedema — a rare disease caused by a congenital deficiency of C1-inhibitor. Clinical manifestations of the disease — recurrent episodes of angioedema, which manifest in childhood or adolescence, more often...
The place of endogenous antimicrobial peptides in the pathogenetic mechanisms of the development of community-acquired pneumonia caused by Streptococcus pneumoniae among infants
A comprehensive survey was carried out in 30 children with community-acquired pneumonia aged 2 months to 3 years old, among them in 18 children the disease was caused by Streptococcus pneumoniae, and in the remaining 12...