Features of Bronchial Asthma Course in Children with Concomitant Gastrointestinal Pathology
Journal Title: Здоров`я дитини - Year 2014, Vol 1, Issue 52
Abstract
Objective. To examine the influence of concomitant gastrointestinal pathology on the course and control of asthma and cytokine status in children with bronchial asthma. Material and methods. The study included 78 children with asthma and concomitant diseases of upper gastrointestinal tract (I group) and 42 children with asthma without upper gastrointestinal tract pathology (II group). The asthma control was estimated according to GINA, 2009. Serum concentrations of cytokines (IFN-γ and IL-4, IL-5, IL-13) were determined by enzyme-linked immunosorbent assay (test sets Diaclone (France). Results. The children with bronchial asthma often have upper gastrointestinal pathology (65 %) that is accompanied with more severe asthma course and low control of its symptoms, especially in H.рylori identification. The children in the group I were found to have an increased IFN-γ and cytokines serum level involved into allergic inflammatory process (IL-4, IL-5) compared with the group II.
Authors and Affiliations
M. V. Kalichevskaya
Keywords
Related Articles
- EP ID EP306142
- DOI -
- Views 78
- Downloads 0
Inhibition of bacterial quorum sensing (general concept)
The scientific review outlines current data characterizing the main provisions on the functioning of the mechanism of the sensory quorum in the system of interbacterial communications. A general characteristic of variou...
Hereditary Fructose Intolerance
Hereditary fructose intolerance, the prevalence of which is 1 : 20,000 population, is diagnosed much less frequently than is found in child and adult populations. Presented pathology is caused by a deficiency in ferment...
Dynamics of neurovegetative regulation in children with recurrent upper respiratory tract infections and reduced myocardial functional reserve after the rehabilitation program
Background. Recently, problems with the level of children’s health cause fears from both the medical and pedagogical community. The intensive school curriculum, the high infectious burden on the younger schoolchild’s org...
The Evidence Base on the Efficacy and Safety of Ibuprofen in Pediatrics
The article deals with an analysis of the world literature of recent years, the aim of which was to study the efficacy and safety of ibuprofen use as first-line antipyretic in pediatric practice. Special attention was pa...
Clinical Observation of a Child with KID (Keratitis-Ichthyosis-Deafness) Syndrome
A clinical case of keratitis-ichthyosis-deafness (KID syndrome) in an infant is described. The article familia-rizes pediatricians and family doctors with difficulties in the diagnosis of this rare genetic disease in inf...