FEATURES OF DETERMINATION OF PROGNOSTIC AND DIAGNICALLY SIGNIFICANT MARKERS IN THE BLOOD OF PATIENTS WITH PULMONARY TUBERCULOSIS
Journal Title: International scientific journal Science and Innovation - Year 2023, Vol 2, Issue 10
Abstract
Throughout the world, the epidemiological situation with regard to tuberculosis remains difficult. Purpose of the study: to study the immunobiological properties of the organism in newly diagnosed patients with pulmonary tuberculosis. We conducted a study on the presence of prognostic and diagnostically significant markers in the blood serum of 30 patients with a verified diagnosis. A comparative group contains 15 practically healthy persons. All patients underwent general clinical, bacterioscopic examination, chest X-ray. It is determined the concentration of cytokines - TNF- α and CRP, VGF. Conclusions: A moderate increase in the level of CRP allows early detection of the course of the pathological process and as certain the formation of a systemic inflammatory response to activate phagocytosis. Correlation of a decrease in the concentration of TNF- α in the blood serum in patients with recurrent disease secondary to an increase in the level of VEGF in the same patients.
Authors and Affiliations
Rustamova S. A. , Muazzamov B. R.
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