Features of Kawasaki disease course in infants
Journal Title: Здоров`я дитини - Year 2019, Vol 14, Issue 6
Abstract
Background. A large number of clinical masks and also insufficient vigilance of doctors regarding Kawasaki syndrome in a child with long-term fever impede timely diagnosis of Kawasaki syndrome. The purpose of the study was to increase the diagnostic efficiency of Kawasaki disease based on a retrospective analysis of its clinical course and outcomes in children under our supervision. Materials and methods. Case histories were analyzed in 7 children aged from 7 months to 6 years, who were treated in the cardiopulmonary department of Children’s Clinical Hospital 2 in Dnipro. The diagnosis of Kawasaki disease was verified based on diagnostic criteria in accordance with the current clinical protocol. Routine research methods and echocardiography were performed for all patients. Results. The study revealed late diagnosis of Kawasaki disease, already at the stage of formation of coronary artery aneurysms, in 43 % of cases. The complexity of diagnosing Kawasaki syndrome was due to the lack of a full range of typical symptoms. The incomplete presentation was noted mainly in children of the first three years of life and included symptoms such as conjunctivitis, maculopapular rash, and oral lesions in various combinations. Echocardiography revealed coronary artery aneurysms in 57 % of cases, mostly in infants with incomplete presentation of Kawasaki disease. Against the background of therapy (intravenous immunoglobulin and aspirin), we observed a significant regression of coronary artery aneurysms in all patients. Conclusions. Infants most often have incomplete presentation of Kawasaki syndrome, which complicates its diagnosis. In this regard, prolonged fever in combination even with 2–3 typical signs should be an absolute indication for echocardiography with mandatory visualization of the coronary arteries.
Authors and Affiliations
O. S. Koreniuk, N. N. Kramarenko, S. H. Ivanus
Keywords
Related Articles
- EP ID EP666675
- DOI 10.22141/2224-0551.14.6.2019.179242
- Views 69
- Downloads 0
Therapeutic Strategy for Chronic Headache in Children
The therapeutic efficacy of a combined homeopathic preparation Cefavora, which consists of alcoholic extracts of Ginkgo biloba, hawthorn (Crataegus) and white mistletoe (Viscum album), has been studied in the treatment o...
Features of Immune Responses in Children with Cerebral Palsy at Sanatorium-Resort Stage of Rehabilitation
Recent years, cases of interruption of sanatorium-resort treatment of children with cerebral palsy (CP) became more often because of acute respiratory infections or exacerbations of chronic inflammatory foci developed in...
Herpes virus 6 hepatitis in an infant
The article presents a clinical observation of 1-year old child diagnosed with hepatitis in the structure of reactivated form of herpes virus type 6 infection. There was a significant increase in transaminase level with...
The Particularities of Airway Hyperresponsiveness to Histamine in Bronchial Asthma School-Age Children in Different Inflammatory Phenotypes
On the base of the Chernivtsy Regional Children Clinical Hospital the diagnostic value of the indices of airway hyperresponsiveness to histamine for a verification of asthma inflammatory phenotypes have been studied in 8...
Current and future etiologic therapy of bacterial pneumonia. 1. Antibiotic therapy for community-acquired pneumonia
The progressive increase in the prevalence of respiratory infections caused by multiresistant pathogenic agents is a serious problem requiring strict indications and development of algorithms for prescribing antibacteria...