Features of management of children with persistent diarrhea and Candida albicans overgrowth
Journal Title: Здоров`я дитини - Year 2019, Vol 14, Issue 0
Abstract
Background: to evaluate the effectiveness of Mutaflor in children from 1 to 4 years of age with a diagnosis of functional gastrointestinal disorders in the form of persistent diarrhea against the background of proven overgrowth of Candida albicans. Materials and methods. The study involved 32 children aged 1 to 4 years with a diagnosis of functional gastrointestinal disorders in the form of persistent diarrhea with proven overgrowth of Candida albicans. Duration of administration of the probiotic agent Mutaflor at a dose of 1 ml of suspension once a day was 15 days. Thirty children completed the follow-up, two patients were excluded from the analysis of results due to non-adherence to treatment protocol. Results. All children had an overgrowth of Candida albicans at baseline. After 15 days of treatment, Candida albicans was detected in the stools of 12 children (40 %), in 11 of them (36.7 %), it was detected in the amount of 104 CFUs, and in one patients (3.3 %) — 103 CFUs indicating that the strain Escherichia coli Nissle 1917 was quite effective for intestinal candidiasis. Conclusions. The use of Mutaflor (Escherichia coli Nissle 1917 probiotic strain) in children with persistent diarrhea against the background of Candida albicans overgrowth contributes to the reduction of diarrhea, colic, abdominal distension, vomiting, episodes of crying/anxiety and poor sleep in children, normalizes intestinal biocenosis.
Authors and Affiliations
S. L. Nyankovskyy, O. S. Nyankovska, Yu. V. Pakulova-Trotska, H. Z. Vivcharivska, V. D. Shaidych, O. M. Horayska, Olha Zastavna, Z. V. Tomkiv
Keywords
Related Articles
- EP ID EP565800
- DOI 10.22141/2224-0551.14.0.2019.165521
- Views 78
- Downloads 0
A case of infantile strongyloidiasis associated with Salmonella infection: diagnostic considerations
Background. Pediatric co-infections are an emerging clinical problem due to their increasing prevalence and tendency to transform a typical clinical presentation of particular diseases. Thereafter, it tangles the accurat...
Pharmacogenetic Aspects of Airways’ Obstruction Relief Therapy of Bronchial Asthma Attacks in Schoolchildren
On the base of a complex examination of 215 schoolchildren who suffer bronchial asthma, there have been established that clinical manifestations of severity of bronchial obstructive syndrome during disease exacerbation d...
Clinical case of recurrent parotitis in a child. Discussion of causes
Currently, with introduction of vaccination against epidemic parotitis, differential diagnosis of salivary gland involvement in children should include other viruses, such as cytomegalovirus, Coxsackie virus, herpes viru...
Differentiated Approach to the Mucolytic Therapy for Respiratory Diseases in Children
This paper presents the mechanisms of disorders of mucociliary clearance in the tracheobronchial tree in respiratory diseases in children. The authors considered differentiated approach to the prescription of mucoactive...
The Efficacy of Levocetirizine in Allergic Rhinitis in Children
Controversies about the preferred treatment of mild persistent or mild-to-moderate intermittent allergic rhinitis were considered in the study involved 62 primary school childrenю They were randomized to receive oral for...