Features of the Clinical Course of Adrenal Incidentalomas
Journal Title: Міжнародний ендокринологічний журнал - Year 2014, Vol 2, Issue 58
Abstract
The objective of the study was to examine the clinical features of adrenal incidentalomas. 98 clinical observations of patients with adrenal incidentalomas receiving in- and out-patient treatment in the clinic of Republican Specialized Scientific and Practical Medical Centre of Endocrinology of Ministry of Healthcare of Republic of Uzbekistan were analyzed. Of them, 51 % — males, 49 % — females. General clinical observation included: thorough gaining of complaints; anamnesis morbi and vitae; assessment of somatic and endocrine statuses; clinical examination with measurement of blood pressure and body mass index; urinalysis; biochemical blood analysis. In addition, all patients underwent complete blood count with determination of blood potassium, sodium, chlorine, lipid profile, fasting blood glucose and oral glucose tolerance test, creatinine and urea; hormonal blood tests, including studies of plasma aldosterone and plasma renin activity in a horizontal position, adrenocorticotropic hormone, blood cortisol, as well as the daily excretion of catecholamines with urine. For topical diagnosis we used ultrasound, CT of adrenals. It was found that adrenal incidentalomas were detected in 37.8 % as a result of searching for the reason of arterial hypertension, in 23.5 % — of obesity and hypothalamus dysfunction, in 14.2 % — in abdominal pathology, in 12.2 % — of non-specific complaints, in 8.1 % — in exclusion of adrenal diseases, and in 4 % — in clinical supervision. Clinically they are characterized with nonspecific features with predominance of arterial hypertension (76.5 %), which is associated with adrenal pathology only 18.4 % of cases. Analysis of metabolic disorders revealed clinically significant changes as well. Of 98 examined patients, 70 % had metabolic disorders.
Authors and Affiliations
G. A. Alimukhamedova
Keywords
Related Articles
- EP ID EP226836
- DOI -
- Views 76
- Downloads 0
Results of the State Diabetes Mellitus Register in Bukhara, Navoi, Khorezm Regions and the Republic of Karakalpakstan
Introduction. Diabetes mellitus (DM) is an important medical and social problem. The objective of the study — to analyze the adequacy of the diagnosis and treatment of patients based on the results of the register in th...
The Point of View of Pathophysiologist-Endocrinologist on the Problem of Age-Related Androgen Deficiency in Men (LOH-Syndrome)
The paper presents a pathophysiological analysis of age-related androgen deficiency syndrome in men (LOH-syndrome) with special reference to current knowledge of molecular mechanisms of testosterone effects and androgen...
Peculiarities of the course and frequency of clinical manifestations of polyglandular syndrome type ІІІА in patients living in the iodine deficient Ternopil region
Background. The problem of early diagnosis of endocrinopathies, such as type 1 diabetes mellitus, autoimmune thyroid disease, adrenal gland disorders on the background of other autoimmune pathologies, remains relevant. O...
Thiamine derivatives and vitamin B1 analogues: biochemical, structural and pathway analysis and its implication in the pathobiology of diabetic complications
Thiamіne acts as a coenzyme for transketolase and for the pyruvate dehydrogenase and α-ketoglutarate dehydrogenase complexes, whіch enzymes play a fundamental role in intracellular glucose metabolіsm. The relatіonship b...
Influence of Endocrine Diseases on Reproductive System Functioning
In the lecture the questions of endocrine diseases influence on the reproductive system functioning are being considered. The reproductive system of woman is analyzed as a complex of interdependent structural elements: h...