Features of the course and treatment of JIA-associated uveitis
Journal Title: Офтальмологический журнал - Year 2019, Vol 0, Issue 2
Abstract
Purpose: To investigate the features of the clinical course of and the state of eye care for patients with juvenile idiopathic arthritis (JIA)-associated uveitis (JIA-U). Materials and Methods: We analyzed the results of monitoring 121 patients aged 7 to 18 years with JIA. Twenty one (17.35%) of these had uveitis. Results: In 17 (80.95%) of the examined JIA-U patients, JIA onset age was younger than 6 years, and mean JIA onset age was significantly younger than in JIA patients without uveitis (2.89±0.26 years vs 6.43±0.4 years, р<0.05). Most (85.7%) JIA-U patients were asymptomatic. Chronic keratic precipitates and posterior synechiae were found in 38.09% and 42.85%, respectively, of cases. Uveal cataract was the most common complication (57.14%), followed by corneal degeneration (33.33%), macular edema (28.57%), ocular hypertension/ secondary glaucoma (19.05%), optic nerve edema (14.28%), hypotony (14.28%), vitreous fibrosis (9.52%), and retinal detachment (4.76%). The frequency of administration of biologics was 57.14%. The mean time from disease onset to administration of biologics in our JIA-U patients (2.67±0.79 years) was 2.5 times less than the value for JIA-U patients from all over Ukraine (6.9 years), indicating that biologics were timely administered. Conclusion: Patients with the condition are commonly asymptomatic and have frequent ocular complications, with uveal cataract being the most common, followed by corneal degeneration and macular edema.
Authors and Affiliations
M. Panchenko, N. Shevchenko, O. Honchar, L. Avilova
Keywords
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- EP ID EP586803
- DOI 10.31288/oftalmolzh201922227
- Views 89
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