Features of the state of the function of the biliary system in helminth parasitic diseases
Journal Title: Здоров`я дитини - Year 2019, Vol 14, Issue 6
Abstract
Pathology of the hepatobiliary tract is widespread throughout the world. When the bile enters the intestine in the inadequate quantity and quality, its peristalsis is disturbed, the walls are irritated, parietal digestion is inadequate and, as a result, malabsorption syndrome and fluid and electrolyte imbalance develop. Helminth parasitic infestations are often the cause of functional disorders. With a prolonged course of functional disorders of the biliary system, conditions are created for the development of organic lesions of the biliary tract, including mechanical occlusion. One of the mechanisms of exposure in helminth parasitic persistence is an increase in the degree of bile lithogenicity as a result of dehydroxylation of bile acids under the influence of microbial enzymes. In this case, chenodeoxycholic acid turns into lithocholic acid, which does not form micelles and, therefore, promotes cholesterol crystallization. Both specific and nonspecific symptoms such as weakness, irritability, mood swings, sleep disorders can indicate damage to the hepatobiliary system of parasitic origin. As a result of the toxic effects of the parasites themselves, products of their decay, drugs aimed at their destruction, the pathology of the hepatobiliary tract develops. In this regard, the comprehensive therapy for helminth parasitic invasions should include drugs that restore the function of the liver and biliary tract. Vormil herbal complex created to eliminate the effects of deworming and to protect against reinfestation, with a unique composition of herbs, has a hepatoprotective, choleretic effect and normalizes gastrointestinal motility. Thus, the use of a combination of Vormil and Vormil Fito herbal complex has an optimal effect in the treatment of helminth parasitic infestations.
Authors and Affiliations
G. A. Zaslavska
Problems of Somatic Pathology in Children with Autistic Spectrum Disorders
Autistic spectrum disorders (ASD) — a complex deviation that is caused by developmental disorders of the brain and is characterized by severe comprehensive deficit of social interaction and communication, as well as rest...
Features of the Physical Development of Children with Bronchopulmonary Dysplasia
We observed 131 children (269 cases) with a diagnosis of bronchopulmonary dysplasia. It is found that children with bronchopulmonary dysplasia are characterized by a delay in weight gain (73.9 ± 2.8 %, p < 0.0001), heigh...
Medical and Rehabilitation Centers in Children’s Houses — New Opportunities for Treatment and Rehabilitation of Children
The article presents data on the opening of medical and rehabilitations centers at the children’s houses of Donetsk region. Approaches, terms, possibilities and methods of rehabilitations used during the treatment and re...
Patent ductus arteriosus: peculiarities of early neonatal, postnatal diagnostics, clinical manifestations, treatment and prognosis
The article presents the published data on the prevalence, the main clinical manifestations, and modern methods of early neonatal and postnatal diagnosis, treatment and prognosis of patent ductus arteriosus — the congeni...
Markers of Airway Remodeling in Bronchopulmonary Diseases
The article presents information about markers of airway remodeling in bronchopulmonary diseases. There is described the influence of matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase, transforming...