FEATURES OF ULTRASTRUCTURAL REARRANGEMENT OF TESTICULAR TISSUES OF RATS AFTER THYROIDECTOMY
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 12
Abstract
Inan experiment in rats treated with thyroidectomy, by usingtheelectron microscopy, it was found that in the postoperative period progressively increase thedystrophic-destructive changes in stromal cells and in parenchymal cells of testicular epithelium. They consist of picnotial deformation of the nuclei, enhanced electron density of the karyoplasm, formation of lysis sites and different sizes of vacuole structures in the cytoplasm with the expansion and fragmentation of the granulum endoplasmic mesh tubules and tubules of the Golgi complex. At the same time, there was a decrease in the content of lipid inclusions and hormonal granules and mitochondria that had an enlightened matrix and often –damaged crystals. Due to the consolidation of the fibrous layer and the cytoplasm of the myoidcells, the walls of the convoluted seminal canals dusted. The basal plate acquired an uneven thickness, microfilaments in it were poorly contoured. Significantly increasedthe intercellular gaps. All these changes occurredonthe background of violation of hemomycrocycle circulation. Moreover, the first daywascharacterized by the narrowing of the lumen of the capillaries with a decrease in their bandwidth. Later on, the lumen of the capillaries markedly expanded and hemomycrocycle disorders became stagnant, which could be the cause of ischemia of the organ as one of the important morphogenetic factors in the development of dystrophic-destructive processes in the parenchymal-stromal components of the testicles. The estimated features of structural reorganization of tissues of the testicle can form the basis of functional insufficiency of this organ.
Authors and Affiliations
Prof. I. Ye. Herasymiuk
Keywords
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