FENTANYL & BUTORPHANOL AS CO-INDUCTION AGENTS FOR LMA INSERTION: A COMPARATIVE STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 36
Abstract
Co Induction Agents for LMA. BACKGROUND: A randomized double blind comparative study was done to assess the effectiveness of fentanyl & butorphanol as coinduction agents with propofol for insertion of Laryngeal Mask Airway (LMA) in adults for elective short surgical procedures. METHODS: Sixty patients of ASA grade 1 and 2 between 15-55 years of age were randomly divided into two groups. After giving standard premedication group A was given injection butorphanol 20 mcg/kg IV and group B injection fentanyl 1.5mcg/kg IV. Both the groups were immediately given propofol 2.5mg/kg IV over 15 seconds until loss of eyelash reflex, after which LMA insertion was performed 60 seconds after injection of propofol. Patients were kept on spontaneous respiration and maintained with isoflurane 0.5%-1.2%, 60%N2O, and 40%O2 along with propofol bolus when required. RESULTS: In our study propofol requirement for LMA insertion was significantly less in butorphanol group and significantly less apnea time was seen with butorphanol (96.66%) as compared to fentanyl (76.66%). The incidence of absolute jaw relaxation was highest in butorphanol (93.33%) and excellent insertion conditions were observed. Best insertion conditions were seen in 92.30% of butorphanol group and 74.15% in fentanyl group. CONCLUSION: The addition of butorphanol to propofol for LMA insertion provides good jaw relaxation and excellent LMA insertion conditions with stable haemodynamics. Side effects like coughing, gagging, lacrimation, and limb movements are lower as compared to the other group. So, butorphanol is a good adjuvant with propofol for LMA insertion during short surgical procedures under general anesthesia.
Authors and Affiliations
Chaula Doshi, Sourabh Phadtare, Gurlyn Ahluwalia, Sunita Swami, Varsha Vyas, Surekha Patil, Jayshree Vaswani, Shubha Mohite
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