Fertility sparing approach as the standard of care in young patients with immature teratomas
Journal Title: UNKNOWN - Year 2017, Vol 18, Issue 1
Abstract
Immature teratomas are quite rare tumors arising in young women. They are usually diagnosed in early stage and grade and have a good prognosis. In these young patients, fertility-sparing management is suggested as the standard of care. Bilateral immature teratoma is a rare condition with an incidence of 10%, with a five-year survival rate of 80%. The majority of patients received fertility-sparing treatment followed by adjuvant chemotherapy in 78%. Older age, advanced stage, and high grade are negative prognostic factors. The surgery-only, watch-and-wait approach was evaluated; however, after a median follow-up time of 42 months, 50% of patients experienced recurrence, but they were successfully salvaged with chemotherapy. In a retrospective study, 12 out of 27 patients tried to conceive, resulting in 10 pregnancies (8 after chemotherapy). We present a narrative review of the current literature regarding the essential multidisciplinary approach of such patients in order to achieve the best oncologic and fertility-sparing outcome.
Authors and Affiliations
Christos Iavazzo, George Vorgias, Paraskevi-Evangelia Iavazzo, Ioannis D. Gkegkes
Keywords
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- EP ID EP379898
- DOI 10.4274/jtgga.2016.0090
- Views 42
- Downloads 0
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