Fetomaternal Outcome in Triplet and Quadruplet Pregnancies: A Retrospective Study
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 6, Issue 6
Abstract
Background: In recent decades, there has been a dramatic increase in the prevalence of multiple pregnancies. An important reason is the increased use of assisted reproductive techniques for conception. Despite the advances in prenatal care, maternal and neonatal morbidity and mortality caused by multiple pregnancies are still high. Aim: This study aimed to evaluate the fetomaternal complications in higher order multiple pregnancies. Design: The design is a retrospective study. Setting: Triplet and quadruplet pregnancies were investigated in this study. Methods: This study investigated the outcome of triplet and quadruplet pregnancies born alive at the Mahdiyeh hospital, Tehran, Iran from 2006 to 2015. Results: In this study, 111 triplet pregnancies and 24 quadruplet pregnancies were studied, 80% of which resulted from assisted reproductive technology. The average age of pregnancy termination was 31 weeks, the average weight of the frst to third neonates was 1400 g and the average weight of the fourth neonate was 700 g. The most common reason for early termination of pregnancy was preterm labor, the most maternal complication was uterine atony and the most common neonatal complication was pre-maturity and then respiratory distress syndrome (RDS). The mean age of mother in triplets’ deliveries was signifcantly lower than in the quadruplets. The average weight of the frst to third neonates, the average of 1st and 5th minutes Apgar score of the frst neonates and the average gestational age of termination for the frst and second neonates in triplets was signifcantly higher than in the quadruplets. Hospitalization due to preterm labor in quadruplets’ delivery was signifcantly higher than in triplets. Conclusion: Higher order multiple pregnancies are associated with higher maternal and neonatal complications. Mothers with such pregnancies needs more care in the prenatal period, during labor and in the postpartum period, and also their neonates need more care after birth, most commonly due to prematurity.
Authors and Affiliations
Maasoumeh Mirzamoradi| Assistant Professor of Perinatology, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Zahra Heidar| Assistant Professor of Infertility, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Maasoumeh Saleh| Department of Gynecology and Obstetrics, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Corresponding e-mail: salehmaasoumeh@yahoo.com
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