Abstract

The American Association of Oral and Maxillofacial Surgeons AAOMS reported in 2004 a new pathology that causes osteonecrosis in the Maxillomandibular complex. The condition was named Bisphosphonate related osteonecrosis of the jaw BRONJ , and later renamed by medication related to jaw osteonecrosis due to the appearance of severe alveolar bone loss in the Maxillomandibular complex resulting from the use of different drugs other than Bisphosphonates. Odontology, especially oral surgery, a field concerned with new biotechnologies, has been introducing innovations in tissue engineering. Oro maxillofacial reconstruction is of great interest to current oral and maxillofacial surgeons, as part of the search for strategies in bioengineering and biomaterials, a major promoter of bio dental research in our times. In order to verify the scientific evidences to analyse the effectiveness of leukocyte and platelet rich fibrin L PRF on bone neoformation in Maxillomandibular complex's surgical procedures, a search for qualified articles was conducted in the Medline PubMed , Embase and Cochrane Central Register of Controlled Trials databases. The works analysed were published from 2013 to 2018. This review concludes that the use of platelet rich fibrin L PRF is significant in the complete healing of the lesion in short postoperative periods and in the resolution of the treatments, reducing the need for postoperative re interventions, resulting in lower morbidity for the patients. by Maria De Fatima Faria | Eric Lucas Dos Santos Cabral | Wilkson Ricardo Silva Castro | Davidson Rogério De Medeiros Florentino | João Florêncio Da Costa Junior | Ricardo Pires De Souza | Fausto Pierdoná Guzen | Francisco Irochima Pinheiro | Amália Cinthia Meneses Rêgo | Irami Araújo-Filho "Fibrin Rich in Leukocytes and Platelets (L-PRF) and Bisphosphonate-Induced Osteonecrosis: We Need to Advertise Now" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23040.pdf Paper URL: https://www.ijtsrd.com/biological-science/other/23040/fibrin-rich-in-leukocytes-and-platelets-l-prf-and-bisphosphonate-induced-osteonecrosis-we-need-to-advertise-now/maria-de-fatima-faria

Authors and Affiliations