Fibroblastic osteosarcoma in a lion (Panthera leo)
Journal Title: Open Veterinary Journal - Year 2014, Vol 1, Issue 1
Abstract
This report describes a case of spontaneous fibroblastic osteosarcoma in the humerus of a lion from a private park in Perugia, Italy. The tumor had an irregular, smooth, brown surface and a generally firm, rubbery consistence with gritty to hard areas interspersed. The mass was poorly vascularized with areas of necrosis at the periphery. The cut surface showed a multilobulated mass that had breached the humeral cortex, with periosteal production of reactive bone. The mass invaded the epiphysis, the synovial membrane, the joint capsule and ligaments. A mild hemorrhagic effusion appeared in the joint space. Clinical signs, gross and histopathologic findings are described in this rare case of a malignant bone tumor.
Authors and Affiliations
L. Leonardi| Dipartimento di Scienze Biopatologiche e Igiene delle Produzioni Animali e Alimentari, Università degli Studi di Perugia, Italy, E. Lepri| Dipartimento di Scienze Biopatologiche e Igiene delle Produzioni Animali e Alimentari, Università degli Studi di Perugia, Italy, S. Nannarone| Dipartimento di Patologia, Diagnostica e Clinica Veterinaria, Università degli Studi di Perugia, Italy, O. Olivieri| Dipartimento di Patologia, Diagnostica e Clinica Veterinaria, Università degli Studi di Perugia, Italy, L. Mechelli| Dipartimento di Scienze Biopatologiche e Igiene delle Produzioni Animali e Alimentari, Università degli Studi di Perugia, Italy
Effectiveness of slow motion video compared to real time video in improving the accuracy and consistency of subjective gait analysis in dogs
Objective measures of canine gait quality via force plates, pressure mats or kinematic analysis are considered superior to subjective gait assessment (SGA). Despite research demonstrating that SGA does not accurately de...
A case of non-regenerative immune-mediated anemia treated by combination therapy of human immune globulin and mycophenolate mofetil in a dog
A 12-year-old female Shih Tzu dog was referred with diarrhea. Hematological examination indicated severe nonregenerative anemia. Bone marrow aspiration smears and core biopsy specimens revealed normal bone marrow. Based...
Reactivity of commercially available monoclonal antibodies to human CD antigens with peripheral blood leucocytes of dromedary camels (Camelus dromedarius)
Monoclonal antibodies (mAbs) to cell surface molecules have been proven as a key tool for phenotypic and functional characterization of the cellular immune response. One of the major difficulties in studying camel cellu...
Isolation of Staphylococcus sciuri from horse skin infection
Staphylococcus sciuri is known as an opportunistic pathogen colonizing domesticated animals and has also been associated with wound infections in humans. Particularly over the last decade, oxacillin (methicillin) resist...
Calcitonin-negative primary neuroendocrine tumor of the thyroid (nonmedullary) in a dog
The Calcitonin-negative neuroendocrine tumor of the thyroid (CNNET) or "nonmedullary" in humans is a rare tumor that arises primarily in the thyroid gland and may be mistaken for medullary thyroid carcinoma; it is chara...