Fifteen-year treatment of metastatic thyroid medullary carcinoma: a case report

Journal Title: The European Research Journal - Year 2015, Vol 1, Issue 3

Abstract

Although very rare, medullary thyroid carcinoma (MTC) is the most aggressive in differentiated thyroid malignancies. We report a 48-year-old male patient with the diagnosis of MTC, who was monitored for fifteen years and showed no serious adverse events due to long-term chemotherapy. Total thyroidectomy, neck dissection, retrosternal nodule excision and pericardiectomy were performed, and radiotherapy was applied to the neck area. Due to progressive metastatic disease cyclophosphamide, dacarbazine, and vincristine were administrated. He tolerated chemotherapy well, and no severe systemic side effects were detected. He died due to multi-organ failure after fifteen years of diagnosis. The only curative treatment is surgery in MTC, however; radiotherapy, chemotherapy, and embolization may be used for patients for whom surgery cannot be performed. Although success rates of systemic chemotherapy are low, it is a treatment option in the progressive metastatic disease.

Authors and Affiliations

Ozen Oz Gul, Soner Cander, Pinar Sisman, Erdinc Erturk, Canan Ersoy

Keywords

Related Articles

The effect of endoscopic sinus surgery on quality of life: a prospective clinical study

Objective. Chronic rhinosinusitis has a negative effect on quality of life of millions of involved patients. The aim of this study was to assess the effect of endoscopic sinus surgery on the quality of life in patients w...

Tingling in tongue due to alprazolam and paroxetine-induced hypergabaergic activity

Paroxetine is a commonly used serotonin-reuptake inhibitor for the treatment of various psychiatric disorders. Available literature is sparse with cases of paresthesia that occur during withdrawal of paroxetine, there ar...

Gastric volvulus: a rare cause of gastric outlet obstruction in pediatric age

Gastric volvulus is a rare disease in the pediatric population. Symptoms may change depending on the type of the disease, rotation degree, and the etiology. Early diagnosis and treatment are important especially in the a...

Could there be any relationship between nutritional deficiencies and idiopathic chest pain in children?

Objectives: Chest pain in childhood is a frequent cause of referral to pediatric cardiology departments although cardiac etiology is very rare. Etiology is usually unidentified and named as ‘idiopatic chest pain’. It is...

The value of cervical mediastinoscopy in the diagnosis of mediastinal lymphadenopathy

Objective. This study retrospectively evaluated mediastinoscopic interventions performed for diagnostic purposes in cases with mediastinal lesions remained undiagnosed by other diagnostic methods. Methods. We retrospecti...

Download PDF file
  • EP ID EP196146
  • DOI 10.18621/eurj.2015.1.3.160
  • Views 102
  • Downloads 0

How To Cite

Ozen Oz Gul, Soner Cander, Pinar Sisman, Erdinc Erturk, Canan Ersoy (2015). Fifteen-year treatment of metastatic thyroid medullary carcinoma: a case report. The European Research Journal, 1(3), 160-164. https://europub.co.uk/articles/-A-196146