First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
Journal Title: Journal Of Pediatric Critical Care - Year 2019, Vol 6, Issue 2
Abstract
Severe sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the fi rst choice of vasoactive agent in adult septic shock fl owed by adrenaline or vasopressin in cases who do not respond to norepinephrine. In this article we have reviewed the literature and compared noradrenaline and adrenaline as fi rst line vasoactive drug in children with fl uid refractory septic shock. We have also discussed the change in the paradigm -use of dopamine as alternative instead of fi rst line vasoactive agent
Authors and Affiliations
Mehak Bansal, Praveen Khilnani
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