Fixed drug eruption induced by moringa oleifera leaf extracts – A case report
Journal Title: Nasza Dermatologia Online - Year 2017, Vol 8, Issue 4
Abstract
Fixed drug eruption (FDE) is a commonly encounter cutaneous drug reaction at the dermatology clinics. The diagnosis is made when a characteristic lesion occurred repeatedly at the same site following re-exposure to the precipitating agent. We are presenting Moringa oleifera as a cause of FDE in a 55 year old man making the plant part of the growing list of implicating agents causing FDE. The mechanism by which it causes the lesion may not be completely understood but may probably be due to high sulphur content in the leaf extracts. The sulphur may serve as hapten and activate CD 8+ effector/memory T- cell leading to generation of proinflammatory cytokines such as interferon-gamma which causes tissue damage.
Authors and Affiliations
Fatai Olatunde Olanrewaju
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