Flash Diagnostic Tool for MDR TB in HIV Era
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 6
Abstract
Abstract: Tuberculosis (TB) is one of the commonest opportunistic infection and the leading cause of death in HIV patients in developing countries. HIV infection is a well recognised risk factor for both activation of initial infection and reactivation of latent infection. This study was done to find out the co-prevalence and the trend of HIV infection among tuberculosis patients and to determine the prevalence of MDR Tuberculosis in HIV positive patients using Xpert MTB/RIF assay (Cepheid, Sunnyvale, CA, United States).The sputum samples are received from patients attending ICTC clinic at Osmania General Hospital, Hyderabad. Sputum specimen was processed for TB detection by Cartridge Based Nucleic Acid Amplification testing (CB-NAAT) using Xpert MTB/RiF assay technology. A total of 125 HIV patients were in the study. Out of these patients 20 MTB cases were detected. Of these 20 cases 18(90%) cases were sensitive to Rifampicin (RIF) and 2(10%) cases were showing resistance to Rifampicin (RIF) drug. Co-existence of HIV and tuberculosis is high and there is high Prevalence of MDR tuberculosis in HIV patients. The Gene Xpert MTB/RIF assay is a novel integrated diagnostic device that performs sample processing and real-time PCR analysis in a single hands-free step for the diagnosis of tuberculosis and rapid detection of RIF resistance in clinical specimens. Keywords:Co- infection, Cartridge based nucleic acid amplification testing, Human immunodeficiency virus (HIV), Rifampicin, Tuberculosis
Authors and Affiliations
S. Rajeshwar Rao, S. Pavani . , G. Sasikala .
Keywords
Related Articles
- EP ID EP371663
- DOI -
- Views 71
- Downloads 0
Diagnosis of Osteopenia and Osteoporosis by Dual Energy X-Ray Absorptiometry
Abstract:This was analytic descriptive study. The aim of this study was to assess the role of the Dual Energy X-ray Absorptiometry scan (DEXA) for lumbar spine and hip joint in diagnosis of osteopenia and osteoprosis. Th...
Prevalence of Allergic Bronchopulmonary Aspergillosis (ABPA) in Patients of Bronchial Asthma in Punjab
True prevalence of ABPA among asthmatics is not known, may be attributed to the lack of a uniform diagnostic criterion and standard tests. To determine the prevalence of ABPA in bronchial asthma. All patients of bronchia...
Somatic Symptom Disorder: Study of Medically Unexplained Symptoms
Somatic symptom disorder is new diagnostic category in DSM 5. Somatic symptom disorder (previously known as somatization disorder) is the association of medically unexplained somatic symptoms with psychological distress...
Study to Find Out Incidence of Cardiac Manifestation in Thyroid Disorder (Hypo and Hyper Both)
Abstract: In summary out of 56 patients of thyroid dysfunction one patient did not have any symptoms suggesting cardiac involvement. 55 patients (98.2 %) had some kind of cardiac symptom. 51 patients (91.07%) had evidenc...
Placental Morphometry in Toxaemia of Pregnancy
Placenta acts as a mirror which reflects intrauterine status of fetus. It is the most accurate record of infant’s prenatal experiences, so study of placenta gives valuable clues in cases of adverse fetal outcome. The stu...