Flavin Containing Monooxygenases and Metabolism of Xenobiotics

Journal Title: Turkish Journal of Pharmaceutical Sciences - Year 2017, Vol 14, Issue 1

Abstract

This review summarizes recent information concerning the pharmacological and toxicological significance of the flavin-containing monooxygenases (FMOs). FMOs are a family of microsomal enzymes involving in the oxygenation of certain xenobiotics and drugs containing nucleophilic heteroatoms. The activities of FMOs in drug metabolism and their relationships with diseases are the areas of research requiring further exploration. Future studies on FMOs may provide considerable information about the pathophysiology of diseases and the information related to this enzyme family may be important for drug designs in future.

Authors and Affiliations

Rahman BAŞARAN, Benay CAN EKE

Keywords

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  • EP ID EP380911
  • DOI 10.4274/tjps.30592
  • Views 142
  • Downloads 0

How To Cite

Rahman BAŞARAN, Benay CAN EKE (2017). Flavin Containing Monooxygenases and Metabolism of Xenobiotics. Turkish Journal of Pharmaceutical Sciences, 14(1), 90-94. https://europub.co.uk/articles/-A-380911