Flavonoid Glycosides from Heracleum pastinaca Fenzl
Journal Title: Turkish Journal of Pharmaceutical Sciences - Year 2019, Vol 16, Issue 2
Abstract
Objectives: The objective was to isolate and characterize the secondary metabolites of Heracleum pastinaca, which has not been previously investigated. Materials and Methods: Conventional chromatographic procedures were carried out for isolation of the compounds. The structures of the compounds were elucidated by extensive 1D and 2D nuclear magnetic resonance spectroscopic analysis in combination with mass spectrometry experiments and comparison with the relevant literature data. Results: This first phytochemical investigation on all parts of H. pastinaca Fenzl led to the isolation and identification of seven known flavonoid glycosides: isoquercetin (1), rutin (2), afzelin (3), astragalin (4), isorhamnetin 3-O-glucoside (5), nicotiflorin (6), and narcissoside (7). Conclusion: This is the first report on the isolation of these flavonoid glycosides from H. pastinaca and compounds 3, 5, 6, and 7 from the genus Heracleum.
Authors and Affiliations
Perihan GÜRBÜZ
Keywords
Related Articles
- EP ID EP548337
- DOI 10.4274/tjps.galenos.2018.53215
- Views 116
- Downloads 0
Comparison of the Essential Oils of Ferula orientalis L., Ferulago sandrasica Peşmen and Quézel, and Hippomarathrum microcarpum Petrov and Their Antimicrobial Activity
Objectives: To determine the chemical composition and antimicrobial activity of the essential oils of the aerial parts of Ferula orientalis L., roots of Ferulago sandrasica Peşmen and Quézel, and aerial parts of Hippomar...
Optimization of Immobilized Aldose Reductase Isolated from Bovine Liver
Objectives: Isolation of enzymes and experiments on them require great effort and cost and are time-consuming. Therefore, it is important to extend the usability of the enzymes by immobilizing them. In this study our pur...
Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing in Turkey
Objectives: The present study aimed to evaluate the antimicrobial and anti-inflammatory activities of methanol extracts and n-hexane, ethyl acetate, chloroform, and water fractions of five Lathyrus species, namely Lathyr...
Design, Formulation and In Vitro Evaluation of Sustained-release Tablet Formulations of Levosulpiride
Objectives: Levosulpiride is a widely used gastroprokinetic agent in the treatment of various gastric disorders; however, its short half-life and increased dosage frequency leads to non-compliance and possible adverse ef...
Preparation and In Vitro Evaluation of Ibuprofen Spherical Agglomerates
Objectives: Ibuprofen, an anti-inflammatory drug, is characterized by poor water solubility, which limits its pharmacologic effects. The present work aimed to the study the effect of agglomeration on the micromeritic pro...