FLOATING MICROSPHERE AS A NOVEL TOOL FOR H2 RECEPTOR BLOCKER
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 2
Abstract
H2 receptor blockers are amongst the most commonly prescribed medications in the world. Almost all the H2 blockers available in the market have severe side effects. As awareness of the local treatment in the stomach, it is necessary to develop the dosage forms which give better release in the stomach. A trend in H2 receptor blocker development has been to improve therapeutic efficacy and reduce the severity of side effects through altering dosage forms by modifying release of the formulations to optimize drug delivery. One such approach is using polymeric microspheres as carriers of drugs. A brief review of the Microsphere, Polymer can be used to formulate microspheres, various methods used to formulate microspheres, in vitro and in vivo evaluation and how H2 receptor blocker are good candidate for this dosage form are briefly given in this article.
Authors and Affiliations
Gaurang Patel, Ajay Tiwari, Nirav Rabadia
Keywords
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