FLOATING MULTI-PARTICULATE ORAL DRUG DELIVERY SYSTEM: A REVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 12
Abstract
The purpose of this review on floating drug delivery systems is the recent literature with mechanism to achieve gastric retention by floatation. Gastroretentive drug delivery system have advantages besides providing better bioavailability to poorly absorbed drugs and a required release profile thus attracting interest of pharmaceutical formulation. These systems are useful to several problems encountered during the development of a pharmaceutical dosage form. The objectives of the review discuss various parameters affecting the behavior of floating multiparticulate oral dosage form and to focus on the recent advances in the field of formulation, characterization, evaluation and applications of floating multi-particulates drug delivery. A large number of marketed formulations are formulated as gastroretentive dosage forms. Floating multi-particulates is one among the several approaches to gastroretention, like flotation, mucoadhesion, sedimentation, expansion, modified shape systems etc. The review also highlights the advantages with reference to the multi-particulate systems, as well as provides an overview of the future prospective that can take place in this arena.
Authors and Affiliations
Manish Jaimini , Vishalkumar Joshi
Keywords
Related Articles
- EP ID EP92995
- DOI -
- Views 99
- Downloads 0
PHARMACOGNOSTICAL STUDY OF NEOLAMRCKAIA CADAMBA (ROXB.) BOSSER BARK
The bark of Neolamarckia cadamba (Roxb.) Bosser Family Rubiaceae is reported to have good medicinal values in traditional system of medicines. The present study deals with pharmacognostical examination of morphological a...
SIMULTANEOUS RATIO DERIVATIVE SPECTROPHOTOMETRIC ESTIMATION OF ACECLOFENAC AND TIZANIDINE WITH PARACETAMOL IN COMBINATION SOLID DOSAGE FORMS
A derivative spectrophotometric procedure has been developed for the simultaneous determination of individual combination of Aceclofenac and Tizanidine with Paracetamol in combined tablet preparation. Tablet extracts of...
JAATYADI GHRITA AND ITS USE IN TREATING VRANA (WOUND)
Ayurveda is an ancient medical science which deals treatment of various diseases, one of them is vrana (wound) which is more common. The vrana is important topic in academic point of view, patient care and research of n...
DESIGN AND CHARACTERIZATION OF COMPRESSION COATED CHRONOMODULATED SYSTEM OF NIFEDIPINE
The main objective of the study was to formulate and evaluate compression coated chronomodulated system of Nifedipine for pulsatile release of the drug. The compression coated systems were prepared by direct compression...
EVALUATION OF ANTHELIMINTIC ACTIVITY IN THE BARK OF Homalium zeylanicum
The main aim of the study was to investigate Phytoconstituents and antihelmintic activity in the bark extract of Homalium zeylanicum. All phytochemical screening methods were done by using standards methods, were as anti...