“FOLLICULAR FLUID INSULIN LIKE GROWTH FACTOR-1 (FF IGF-1) IS A BIOCHEMICAL MARKER OF EMBRYONIC HEALTH AND IMPLANTATION RATES IN IVF CYCLES”
Journal Title: INTERNATIONAL JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH - Year 2014, Vol 2, Issue 5
Abstract
Health of embryo may be a major determinant of its implantation potential in IVF cycles. IGF-1 has been reported to play a role in human follicular and embryonic development. However, earlier studies carried out mostly in animal models or in culture mediums supplemented with IGF-1 have been unable to directly link IGF-1 with embryo quality. Results correlating IGF-1 with pregnancy outcome have also been ambiguous so far. Therefore, objective of this study was to find if in-situ follicular-fluid level of IGF-1 may be a marker of embryonic health and implantation rates in IVF cycles
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