Following up and re-entry of HBV reactive blood donors in Yantai area
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 8
Abstract
Objective To analyze the preliminary screening and follow-up testing data of HBV in Yantai area, and discuss the rationality of following up and re-entry program of HBV reactive blood donors. Methods Donors who were single reagent reactive by enzyme-linked immunosorbent assay (ELISA) in initial screening but non-reactive by nucleic acid testing (NAT) were followed up. Individual NAT(ID-NAT) was performed for HBV DNA, ELISA for HBsAg, HBsAb, HBeAb, HBeAg and HBcAb, and ECLIA for the detection of HBsAg. Results A total of 547 blood donors were HBsAg ELISA-/NAT+, and 97 were followed up, among which 24 met the requirements of re-entry while 73 did not. Of the 24 blood donors who met the re-entry requirements, 13 donated blood again, with test results all qualified. Conclusion The combination of ELISA, ID-NAT, and ECLIA methods for following up detection for HBsAg ELISA+ blood donors is recommended. Blood donors with HbsAb S/CO ≥ 10 and negative results for other tests met the re-entry requirements, with a re-entry rate at 24.74%, and the re-donation qualified rate of blood donors after re-entry was 100%.
Authors and Affiliations
Hewei SONG, Xintang SHEN, Wei WANG, Minghua XU
Keywords
Related Articles
- EP ID EP738617
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.08.014
- Views 42
- Downloads 0
Investigation on the incidence and risk factors of fetomaternal hemorrhage syndrome in pregnant women in Changsha
Objective To investigate the incidence and possible risk factors of FMH among pregnant women in Changsha. Methods A total of pregnant women (6~42 weeks of gestation) who underwent prenatal examinations in our hospital fr...
Identification of B(A) subtype and analysis of bood transfusion strategiaes
Objective To investigate the serology and genotype identification method of B (A) subtype patients. Methods Test tube method (serology) was used to confirm the clinically difficult ABO blood group samples of 3 patients w...
Validation of the detection method for residual human coagulation factor Ⅺ in human prothrombin complex
Objective To establish an enzyme-linked immunosorbent assay (ELISA) method for the determination of residual human coagulation factor Ⅺ in human prothrombin complex and validate the method. Methods Human factor Ⅺ was rea...
Efficacy of apheresis and concentrated platelets under different transfusion strategies
Objective To retrospectively analyze the clinical effects of apheresis and concentrated platelets under different transfusion strategies, so as to explore more scientific transfusion strategies. Methods A total of 279 pa...
Establishment of the maximum surgical blood order schedule for cesarean sections
Objective To establish the catalog of maximum surgical blood order schedule(MSBOS) for cesarean sections with different obstetric complications, so as to guide the doctors of clinical and Blood Transfusion Department to...