Formulation and Evaluation of Herbal Gel Containing Terminalia chebula Retz., Leaves Extract
Journal Title: Scholars Academic Journal of Pharmacy - Year 2015, Vol 4, Issue 3
Abstract
In this context a technique was employed for the formulation of herbal gel by using Terminalia chebula Retz.,. The plant is commonly referred as ‘King of Medicine’ in Tibet, which is widely grown at places up to a height of about 2000 m from the sea level, and in areas with an annual rainfall 100-150 cm and temperature 0-17° C in tropical and subtropical regions of East Asia. It mainly contains active constituents like steroids, flavonoids, tannins, reducing sugar, belleric acid, bellericoside, chebulinic acid, gallic acid, ethyl gallate,punicalagin, terflavin A, terchebin, luteolin, and tannic acid . It is mainly used as antibacterial and antifungal, analgesic, anti-inflammatoy, sun burns and wound healing. Various formulations were prepared with different concentrations of the plant extract and it was evaluated for physical parameters, viscosity, Skin Irritation and Spreadibility. Out of the three formulations the 5% was found to be better in all aspects. Thus it can be used as an alternative for the treatments and drug delivery systems. Keywords: Terminalia chebula Retz., aqueous extract, Carbapol 940, herbal Gel, skin irritation.
Authors and Affiliations
R. Bhramaramba, I Sudheer Babu, Ch. Divya Naga Deepthi
Keywords
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