FORMULATION AND EVALUATION OF TABLETS CONTAINING ARTEMETHER MICROSPHERES AND LUMEFANTRINE
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 7
Abstract
This study was aimed to fabricate and evaluate a combination of Artemether and Lumefantrine as tablets and to make Artemether in sustained form so as to prolong its elimination time. Artemether was formulated in form of microspheres by solvent evaporation technique and was then formed into the tablet along with the Lumefantrine. Artemether microspheres were prepared and compressed into compressible tablet by direct compression process using the compressible excipients along with Lumefantrine, and was further evaluated for various parameters such as hardness, thickness, weight variation, friability, drug content, in vitro drug release and stability.
Authors and Affiliations
Kuldeep Vinchurkar
Keywords
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- EP ID EP296874
- DOI 10.22270/jddt.v7i7.1569
- Views 133
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