Fournier’s Gangrene: Experience with 147 Patients From A Single Surgical Unit and Identification of the Prognostic Factors
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 12
Abstract
BACKGROUND: Many studies are available in the literature regarding Fournier’s Gangrene but this is a prospective analysis of patients with Fournier’s gangrene in 147 patients in a single surgical unit in a period of 14 years. METHODS: A prospective study of all patient of Fournier’s Gangrene admitted in one surgical unit in a period of 14 years in a University Hospital in North East part of India and the etiology, predisposing factors, management outcome and predictors of mortality were analyzed. RESULTS: Of 147 patients, two were females. Mean age of presentation was 48.4 years Source of infection was identified as scrotal (36), anorectal (29) or urogenital (27), but in 55 patients, source could not be identified. The predisposing factor were diabetes in 51 , alcoholism in 28, immunosuppression in 10, renal failure in 5, malignancy in 2 and portal hypertension in 1. In 50 patients, no predisposing factor could be identified. In 80 patients, the infection was polymicrobial with two to three microbes. Mortality rate was 20.4% (n=30) & mean hospital stay was 36.5 days (Range 11 to 68 days). Leukocytosis, low hemoglobin , increased serum creatinine, diabetes and involvement of perineum and abdominal wall were associated with increased mortality. CONCLUSIONS: Fournier’s gangrene is usually associated with underlying systemic disorder and frequently underlying source of infection is present. Leukocytosis, high creatinine, low hemoglobin, diabetes and involvement of perineum and abdominal wall are associated with increased mortality.
Authors and Affiliations
Dr. Satyendra K Tiwary, Dr Ram Niwas Meena, Dr. Puneet Kumar, Dr. Ajay K Khanna
Keywords
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